Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Hpx

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hpx ( synonyms: Hpxn, hx )
Protein Name(s) hemopexin,
External Links
MGI MGI:105112

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002639

positive regulation of immunoglobulin production

MGI:MGI:3807609
PMID:18641331[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447193

P

From MGI

GO:0002925

positive regulation of humoral immune response mediated by circulating immunoglobulin

MGI:MGI:3807609
PMID:18641331[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447193

P

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005615

extracellular space

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P02790

C

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0020027

hemoglobin metabolic process

MGI:MGI:1350473
PMID:10572107[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447193

P

From MGI

GO:0020037

heme binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P20058

F

From MGI

GO:0042168

heme metabolic process

MGI:MGI:3799398
PMID:18556779[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447193

P

From MGI

GO:0042511

positive regulation of tyrosine phosphorylation of Stat1 protein

MGI:MGI:3807609
PMID:18641331[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447193

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0051246

regulation of protein metabolic process

MGI:MGI:1350473
PMID:10572107[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447193

P

From MGI

GO:0060332

positive regulation of response to interferon-gamma

MGI:MGI:3807609
PMID:18641331[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447193

P

From MGI

GO:0060335

positive regulation of interferon-gamma-mediated signaling pathway

MGI:MGI:3807609
PMID:18641331[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2447193

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Fagoonee S et al. (2008) Lack of plasma protein hemopexin dampens mercury-induced autoimmune response in mice. J Immunol 181: 1937-47 PubMed GONUTS page
  2. 2.0 2.1 Tolosano E et al. (1999) Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice. Blood 94: 3906-14 PubMed GONUTS page
  3. Vinchi F et al. (2008) Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload. Am J Pathol 173: 289-99 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox