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MGI:Hpse
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hpse ( synonyms: Hpa ) | |
| Protein Name(s) | heparanase, | |
| External Links | ||
| MGI | MGI:1343124 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:1339897 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3574236 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3721153 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005764 |
lysosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005975 |
carbohydrate metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0130 |
P |
From MGI |
||
| GO:0007160 |
cell-matrix adhesion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010575 |
positive regulation vascular endothelial growth factor production |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0016798 |
hydrolase activity, acting on glycosyl bonds |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030194 |
positive regulation of blood coagulation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030305 |
heparanase activity |
MGI:MGI:1339897 |
ISO: Inferred from Sequence Orthology |
EMBL:AF165154 |
F |
From MGI |
||
| GO:0030305 |
heparanase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_072127 |
F |
From MGI |
||
| GO:0033690 |
positive regulation of osteoblast proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0033690 |
positive regulation of osteoblast proliferation |
MGI:MGI:5284762 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042060 |
wound healing |
MGI:MGI:3574236 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043169 |
cation binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0045121 |
membrane raft |
MGI:MGI:3721153 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045545 |
syndecan binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046983 |
protein dimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051797 |
regulation of hair follicle development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051798 |
positive regulation of hair follicle development |
MGI:MGI:3574236 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051897 |
positive regulation of protein kinase B signaling cascade |
MGI:MGI:3721153 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051897 |
positive regulation of protein kinase B signaling cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060055 |
angiogenesis involved in wound healing |
MGI:MGI:3574236 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0061042 |
vascular wound healing |
MGI:MGI:3574236 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hulett MD et al. (1999) Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis. Nat Med 5: 803-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Zcharia E et al. (2005) Heparanase regulates murine hair growth. Am J Pathol 166: 999-1008 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Ben-Zaken O et al. (2007) Heparanase induces Akt phosphorylation via a lipid raft receptor. Biochem Biophys Res Commun 361: 829-34 PubMed GONUTS page
- ↑ Brown AJ et al. (2008) Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation. Bone 43: 689-99 PubMed GONUTS page
