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MGI:Hoxb3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hoxb3 ( synonyms: Hox-2.7 )
Protein Name(s) homeobox B3,
External Links
MGI MGI:96184

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4949985
PMID:21320481[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000979

RNA polymerase II core promoter sequence-specific DNA binding

MGI:MGI:4949985
PMID:21320481[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001827
InterPro:IPR009057

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001827
InterPro:IPR001356

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005634

nucleus

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001827
InterPro:IPR017970
InterPro:IPR001356

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:1195045
PMID:9441667[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:96175
MGI:MGI:96207

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:1859107
PMID:10885747[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:96183
MGI:MGI:96182
MGI:MGI:96185
MGI:MGI:96186
MGI:MGI:96187
MGI:MGI:96188
MGI:MGI:96189
MGI:MGI:96190

P

From MGI

GO:0021546

rhombomere development

MGI:MGI:4949985
PMID:21320481[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0021615

glossopharyngeal nerve morphogenesis

MGI:MGI:1195045
PMID:9441667[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:96175
MGI:MGI:96207

P

From MGI

GO:0030878

thyroid gland development

MGI:MGI:1201272
PMID:9520319[4]

IGI: Inferred from Genetic Interaction

MGI:MGI:96175

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

F

From MGI

GO:0048704

embryonic skeletal system morphogenesis

MGI:MGI:1195045
PMID:9441667[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:96175
MGI:MGI:96207

P

From MGI

GO:0048704

embryonic skeletal system morphogenesis

MGI:MGI:1195045
PMID:9441667[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2151773

P

From MGI

GO:0048704

embryonic skeletal system morphogenesis

MGI:MGI:1859107
PMID:10885747[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:96183
MGI:MGI:96182
MGI:MGI:96185
MGI:MGI:96186
MGI:MGI:96187
MGI:MGI:96188
MGI:MGI:96189
MGI:MGI:96190

P

From MGI

GO:0050767

regulation of neurogenesis

MGI:MGI:4949985
PMID:21320481[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0051216

cartilage development

MGI:MGI:1195045
PMID:9441667[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:96175
MGI:MGI:96207

P

From MGI

GO:0060216

definitive hemopoiesis

MGI:MGI:3761081
PMID:17761289[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:96180
MGI:MGI:96185

P

From MGI

GO:0060324

face development

MGI:MGI:4949985
PMID:21320481[1]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Wong EY et al. (2011) Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning. Dev Biol 352: 382-92 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Manley NR & Capecchi MR (1997) Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Dev Biol 192: 274-88 PubMed GONUTS page
  3. 3.0 3.1 Medina-Martínez O et al. (2000) A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations. Dev Biol 222: 71-83 PubMed GONUTS page
  4. Manley NR & Capecchi MR (1998) Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. Dev Biol 195: 1-15 PubMed GONUTS page
  5. Magnusson M et al. (2007) Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects. Exp Hematol 35: 1421-8 PubMed GONUTS page
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