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MGI:Hoxb1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hoxb1 ( synonyms: Hox-2.9 ) | |
| Protein Name(s) | homeobox B1, | |
| External Links | ||
| MGI | MGI:96182 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:67108 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0009653 |
anatomical structure morphogenesis |
MGI:MGI:1346308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96170 |
P |
From MGI |
||
| GO:0009952 |
anterior/posterior pattern specification |
MGI:MGI:1346308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96170 |
P |
From MGI |
||
| GO:0009952 |
anterior/posterior pattern specification |
MGI:MGI:1859107 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96183 |
P |
From MGI |
||
| GO:0019904 |
protein domain specific binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0021546 |
rhombomere development |
MGI:MGI:4949985 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0021570 |
rhombomere 4 development |
MGI:MGI:1346308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96170 |
P |
From MGI |
||
| GO:0021571 |
rhombomere 5 development |
MGI:MGI:1346308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96170 |
P |
From MGI |
||
| GO:0021612 |
facial nerve structural organization |
MGI:MGI:83677 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857824 |
P |
From MGI |
||
| GO:0021754 |
facial nucleus development |
MGI:MGI:83677 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857824 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:3817812 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97495 |
F |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3817812 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048646 |
anatomical structure formation involved in morphogenesis |
MGI:MGI:1346308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96170 |
P |
From MGI |
||
| GO:0048704 |
embryonic skeletal system morphogenesis |
MGI:MGI:1859107 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96183 |
P |
From MGI |
||
|
contributes_to |
GO:0003677 |
DNA binding |
MGI:MGI:894947 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Pellerin I et al. (1994) Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster. Mol Cell Biol 14: 4532-45 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Rossel M & Capecchi MR (1999) Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development 126: 5027-40 PubMed GONUTS page
- ↑ 3.0 3.1 Medina-Martínez O et al. (2000) A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations. Dev Biol 222: 71-83 PubMed GONUTS page
- ↑ Wong EY et al. (2011) Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning. Dev Biol 352: 382-92 PubMed GONUTS page
- ↑ 5.0 5.1 Goddard JM et al. (1996) Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve. Development 122: 3217-28 PubMed GONUTS page
- ↑ 6.0 6.1 Wassef MA et al. (2008) Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors. Development 135: 3369-78 PubMed GONUTS page
- ↑ Maconochie MK et al. (1997) Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1. Genes Dev 11: 1885-95 PubMed GONUTS page