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MGI:Hoxa13
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hoxa13 ( synonyms: Hox-1.10 ) | |
| Protein Name(s) | homeobox A13, | |
| External Links | ||
| MGI | MGI:96173 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001570 |
vasculogenesis |
MGI:MGI:3797428 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0001886 |
endothelial cell morphogenesis |
MGI:MGI:3797428 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0001894 |
tissue homeostasis |
MGI:MGI:3797428 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0003281 |
ventricular septum development |
MGI:MGI:3797428 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:3829797 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3620476 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3527920 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3527920 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3530958 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0009653 |
anatomical structure morphogenesis |
MGI:MGI:2662001 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0009887 |
organ morphogenesis |
MGI:MGI:1336094 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857336 |
P |
From MGI |
||
| GO:0030510 |
regulation of BMP signaling pathway |
MGI:MGI:2662001 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0030539 |
male genitalia development |
MGI:MGI:2662001 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0035115 |
embryonic forelimb morphogenesis |
MGI:MGI:3530958 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2150506 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:2662001 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:3797428 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0045840 |
positive regulation of mitosis |
MGI:MGI:2662001 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3620476 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3797428 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0048619 |
embryonic hindgut morphogenesis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:XP_002726421 |
P |
From MGI |
||
| GO:0048839 |
inner ear development |
MGI:MGI:3797428 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0048844 |
artery morphogenesis |
MGI:MGI:3797428 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
||
| GO:0060442 |
branching involved in prostate gland morphogenesis |
MGI:MGI:1336094 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857336 |
P |
From MGI |
||
| GO:0060847 |
endothelial cell fate specification |
MGI:MGI:3797428 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152356 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Shaut CA et al. (2008) HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification. PLoS Genet 4: e1000073 PubMed GONUTS page
- ↑ Kawakami Y et al. (2009) Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities. Development 136: 585-94 PubMed GONUTS page
- ↑ 3.0 3.1 Salsi V & Zappavigna V (2006) Hoxd13 and Hoxa13 directly control the expression of the EphA7 Ephrin tyrosine kinase receptor in developing limbs. J Biol Chem 281: 1992-9 PubMed GONUTS page
- ↑ 4.0 4.1 Williams TM et al. (2005) Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction. Dev Biol 277: 457-71 PubMed GONUTS page
- ↑ 5.0 5.1 Williams TM et al. (2005) Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability. Dev Biol 279: 462-80 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 Morgan EA et al. (2003) Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development 130: 3095-109 PubMed GONUTS page
- ↑ 7.0 7.1 Podlasek CA et al. (1999) Hoxa-13 gene mutation results in abnormal seminal vesicle and prostate development. J Urol 161: 1655-61 PubMed GONUTS page
