GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Hoxa11
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hoxa11 ( synonyms: Hox-1.9, Hoxa-11 ) | |
| Protein Name(s) | homeobox A11, | |
| External Links | ||
| MGI | MGI:96172 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001501 |
skeletal system development |
MGI:MGI:2667742 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96193 |
P |
From MGI |
||
| GO:0001501 |
skeletal system development |
MGI:MGI:73938 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1934269 |
P |
From MGI |
||
| GO:0001656 |
metanephros development |
MGI:MGI:3036921 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
||
| GO:0001658 |
branching involved in ureteric bud morphogenesis |
MGI:MGI:2135652 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
||
| GO:0001759 |
organ induction |
MGI:MGI:3036921 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2177896 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3038045 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:1098387 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:2177896 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007501 |
mesodermal cell fate specification |
MGI:MGI:3768605 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009952 |
anterior/posterior pattern specification |
MGI:MGI:2667742 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96193 |
P |
From MGI |
||
| GO:0009953 |
dorsal/ventral pattern formation |
MGI:MGI:2135652 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
||
| GO:0009954 |
proximal/distal pattern formation |
MGI:MGI:2667742 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96193 |
P |
From MGI |
||
| GO:0010720 |
positive regulation of cell development |
MGI:MGI:3043491 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
||
| GO:0030326 |
embryonic limb morphogenesis |
MGI:MGI:3043491 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
||
| GO:0032332 |
positive regulation of chondrocyte differentiation |
MGI:MGI:3043491 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
||
| GO:0032993 |
protein-DNA complex |
MGI:MGI:3768605 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042733 |
embryonic digit morphogenesis |
MGI:MGI:2667742 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96193 |
P |
From MGI |
||
| GO:0043234 |
protein complex |
MGI:MGI:3768605 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3768605 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048589 |
developmental growth |
MGI:MGI:3043491 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
||
| GO:0060351 |
cartilage development involved in endochondral bone morphogenesis |
MGI:MGI:3043491 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96203 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Wellik DM & Capecchi MR (2003) Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton. Science 301: 363-7 PubMed GONUTS page
- ↑ Davis AP et al. (1995) Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11. Nature 375: 791-5 PubMed GONUTS page
- ↑ 3.0 3.1 Wellik DM et al. (2002) Hox11 paralogous genes are essential for metanephric kidney induction. Genes Dev 16: 1423-32 PubMed GONUTS page
- ↑ 4.0 4.1 Patterson LT et al. (2001) Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney. Development 128: 2153-61 PubMed GONUTS page
- ↑ 5.0 5.1 Zhao Y & Potter SS (2002) Functional comparison of the Hoxa 4, Hoxa 10, and Hoxa 11 homeoboxes. Dev Biol 244: 21-36 PubMed GONUTS page
- ↑ Luo L et al. (2004) The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions. Nature 427: 749-53 PubMed GONUTS page
- ↑ Shen WF et al. (1997) AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Mol Cell Biol 17: 6448-58 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Gong KQ et al. (2007) A Hox-Eya-Pax complex regulates early kidney developmental gene expression. Mol Cell Biol 27: 7661-8 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 Boulet AM & Capecchi MR (2004) Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod. Development 131: 299-309 PubMed GONUTS page
