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MGI:Hmx3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hmx3 ( synonyms: Nkx5-1, Nkx5.1 )
Protein Name(s) H6 homeobox 3,
External Links
MGI MGI:107160

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009057

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005634

nucleus

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0007420

brain development

MGI:MGI:3055237
PMID:15363417[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:107159

P

From MGI

GO:0007566

embryo implantation

MGI:MGI:1197796
PMID:9435283[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857577

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0042472

inner ear morphogenesis

MGI:MGI:1197796
PMID:9435283[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857577

P

From MGI

GO:0042472

inner ear morphogenesis

MGI:MGI:3055237
PMID:15363417[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:107159

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:3773266
PMID:10206974[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0050885

neuromuscular process controlling balance

MGI:MGI:1197796
PMID:9435283[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857577

P

From MGI

GO:0060135

maternal process involved in female pregnancy

MGI:MGI:1197796
PMID:9435283[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857577

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Wang W et al. (2004) Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx. Dev Cell 7: 439-53 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Wang W et al. (1998) Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene. Development 125: 621-34 PubMed GONUTS page
  3. Amendt BA et al. (1999) Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA-binding site. J Biol Chem 274: 11635-42 PubMed GONUTS page
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