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MGI:Hip1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hip1 ( synonyms: HIP-1 ) | |
| Protein Name(s) | huntingtin interacting protein 1, | |
| External Links | ||
| MGI | MGI:1099804 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003779 |
actin binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0009 |
F |
From MGI |
||
| GO:0003779 |
actin binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2667266 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3703280 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005543 |
phospholipid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:2657118 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006897 |
endocytosis |
MGI:MGI:2153333 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:2657118 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:2657118 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008219 |
cell death |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0523 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0030136 |
clathrin-coated vesicle |
MGI:MGI:2154594 |
ISO: Inferred from Sequence Orthology |
EMBL:AF388529 |
C |
From MGI |
||
| GO:0030136 |
clathrin-coated vesicle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030276 |
clathrin binding |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
EMBL:AF388529 |
F |
From MGI |
||
| GO:0030276 |
clathrin binding |
MGI:MGI:2154594 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030276 |
clathrin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001093945 |
F |
From MGI |
||
| GO:0031410 |
cytoplasmic vesicle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0968 |
C |
From MGI |
||
| GO:0035091 |
phosphatidylinositol binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:2657118 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043231 |
intracellular membrane-bounded organelle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0048260 |
positive regulation of receptor-mediated endocytosis |
MGI:MGI:2154594 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0048260 |
positive regulation of receptor-mediated endocytosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048268 |
clathrin coat assembly |
MGI:MGI:2154594 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048268 |
clathrin coat assembly |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001093945 |
P |
From MGI |
||
| GO:0048268 |
clathrin coat assembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Metzler M et al. (2003) Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking. EMBO J 22: 3254-66 PubMed GONUTS page
- ↑ Metzler M et al. (2007) NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1. J Neurosci 27: 2298-308 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gervais FG et al. (2002) Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat Cell Biol 4: 95-105 PubMed GONUTS page
- ↑ Rao DS et al. (2001) Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors. Mol Cell Biol 21: 7796-806 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Mishra SK et al. (2001) Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins. J Biol Chem 276: 46230-6 PubMed GONUTS page
