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MGI:Hfe
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hfe ( synonyms: MR2 ) | |
| Protein Name(s) | hemochromatosis, | |
| External Links | ||
| MGI | MGI:109191 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002474 |
antigen processing and presentation of peptide antigen via MHC class I |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0490 |
P |
From MGI |
||
| GO:0005769 |
early endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006955 |
immune response |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0019882 |
antigen processing and presentation |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0031410 |
cytoplasmic vesicle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042446 |
hormone biosynthetic process |
MGI:MGI:3700581 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385353 |
P |
From MGI |
||
| GO:0042612 |
MHC class I protein complex |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0490 |
C |
From MGI |
||
| GO:0042612 |
MHC class I protein complex |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0045177 |
apical part of cell |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045177 |
apical part of cell |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045178 |
basal part of cell |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0055037 |
recycling endosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0055072 |
iron ion homeostasis |
MGI:MGI:3700581 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2385353 |
P |
From MGI |
||
| GO:0060586 |
multicellular organismal iron ion homeostasis |
MGI:MGI:1332955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181388 |
P |
From MGI |
||
|
NOT |
GO:0031528 |
microvillus membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Makui H et al. (2005) Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading. Blood 106: 2189-95 PubMed GONUTS page
- ↑ Fleming RE et al. (1999) Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1. Proc Natl Acad Sci U S A 96: 3143-8 PubMed GONUTS page
