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MGI:Hesx1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hesx1 ( synonyms: HES-1, Rpx ) | |
| Protein Name(s) | homeobox gene expressed in ES cells, | |
| External Links | ||
| MGI | MGI:96071 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:3690195 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3778150 |
IPI: Inferred from Physical Interaction |
UniProtKB:P13864 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:3778150 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007420 |
brain development |
MGI:MGI:2157655 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1931124 |
P |
From MGI |
||
| GO:0008022 |
protein C-terminus binding |
MGI:MGI:3778150 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:5284777 |
NAS: Non-traceable Author Statement |
F |
From MGI |
|||
| GO:0030916 |
otic vesicle formation |
MGI:MGI:1206234 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1931124 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0043584 |
nose development |
MGI:MGI:1206234 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1931124 |
P |
From MGI |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3778150 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0047485 |
protein N-terminus binding |
MGI:MGI:3778150 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0048853 |
forebrain morphogenesis |
MGI:MGI:1206234 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1931124 |
P |
From MGI |
||
| GO:0048853 |
forebrain morphogenesis |
MGI:MGI:1861369 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1931124 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Olson LE et al. (2006) Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell 125: 593-605 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Sajedi E et al. (2008) DNMT1 interacts with the developmental transcriptional repressor HESX1. Biochim Biophys Acta 1783: 131-43 PubMed GONUTS page
- ↑ Martinez-Barbera JP & Beddington RS (2001) Getting your head around Hex and Hesx1: forebrain formation in mouse. Int J Dev Biol 45: 327-36 PubMed GONUTS page
- ↑ Katoh M & Katoh M (2007) Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. Int J Oncol 31: 461-6 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Dattani MT et al. (1998) Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse. Nat Genet 19: 125-33 PubMed GONUTS page
- ↑ Martinez-Barbera JP et al. (2000) The homeobox gene Hesx1 is required in the anterior neural ectoderm for normal forebrain formation. Dev Biol 223: 422-30 PubMed GONUTS page
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