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MGI:Hes7
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hes7 ( synonyms: bHLHb37 ) | |
| Protein Name(s) | hairy and enhancer of split 7 (Drosophila), | |
| External Links | ||
| MGI | MGI:2135679 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:1932412 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3046002 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3578712 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001501 |
skeletal system development |
MGI:MGI:2152470 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2652222 |
P |
From MGI |
||
| GO:0001756 |
somitogenesis |
MGI:MGI:2152470 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2652222 |
P |
From MGI |
||
| GO:0001756 |
somitogenesis |
MGI:MGI:3046002 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2652222 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007219 |
Notch signaling pathway |
MGI:MGI:1932412 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0008134 |
transcription factor binding |
MGI:MGI:5284777 |
NAS: Non-traceable Author Statement |
F |
From MGI |
|||
| GO:0035121 |
tail morphogenesis |
MGI:MGI:2152470 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2652222 |
P |
From MGI |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:2664435 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4943377 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048511 |
rhythmic process |
MGI:MGI:2152470 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048511 |
rhythmic process |
MGI:MGI:3046002 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2652222 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Bessho Y et al. (2001) Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm. Genes Cells 6: 175-85 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Hirata H et al. (2004) Instability of Hes7 protein is crucial for the somite segmentation clock. Nat Genet 36: 750-4 PubMed GONUTS page
- ↑ Morimoto M et al. (2005) The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature 435: 354-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Bessho Y et al. (2001) Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev 15: 2642-7 PubMed GONUTS page
- ↑ Katoh M & Katoh M (2007) Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. Int J Oncol 31: 461-6 PubMed GONUTS page
- ↑ Bessho Y et al. (2003) Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev 17: 1451-6 PubMed GONUTS page
- ↑ Sparrow DB et al. (2008) Mutation of Hairy-and-Enhancer-of-Split-7 in humans causes spondylocostal dysostosis. Hum Mol Genet 17: 3761-6 PubMed GONUTS page
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