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MGI:Helt
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Helt ( synonyms: Heslike, megane ) | |
| Protein Name(s) | helt bHLH transcription factor, | |
| External Links | ||
| MGI | MGI:3040955 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3040538 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001967 |
suckling behavior |
MGI:MGI:3702791 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3703237 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:3040538 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3040538 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3040538 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3640904 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:3040538 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0007417 |
central nervous system development |
MGI:MGI:3702791 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3703237 |
P |
From MGI |
||
| GO:0009791 |
post-embryonic development |
MGI:MGI:3702791 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3703237 |
P |
From MGI |
||
| GO:0010259 |
multicellular organismal aging |
MGI:MGI:3702791 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3703237 |
P |
From MGI |
||
| GO:0010467 |
gene expression |
MGI:MGI:3702791 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3703237 |
P |
From MGI |
||
| GO:0021858 |
GABAergic neuron differentiation in basal ganglia |
MGI:MGI:3702791 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3703237 |
P |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030182 |
neuron differentiation |
MGI:MGI:3042488 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96919 |
P |
From MGI |
||
| GO:0035264 |
multicellular organism growth |
MGI:MGI:3702791 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3703237 |
P |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:3040538 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Nakatani T et al. (2004) Helt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous system. J Biol Chem 279: 16356-67 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Guimera J et al. (2006) Megane/Heslike is required for normal GABAergic differentiation in the mouse superior colliculus. Development 133: 3847-57 PubMed GONUTS page
- ↑ Guimera J et al. (2006) Molecular characterization, structure and developmental expression of Megane bHLH factor. Gene 377: 65-76 PubMed GONUTS page
- ↑ Miyoshi G et al. (2004) Identification of a novel basic helix-loop-helix gene, Heslike, and its role in GABAergic neurogenesis. J Neurosci 24: 3672-82 PubMed GONUTS page
