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MGI:Hdac9

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hdac9 ( synonyms: Hdac7b, HDRP, Mitr )
Protein Name(s) histone deacetylase 9,
External Links
MGI MGI:1931221

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000118

histone deacetylase complex

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

C

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:2136109
PMID:11390982[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:3621255
PMID:16280321[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0003714

transcription corepressor activity

MGI:MGI:1931108
PMID:11022042[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004407

histone deacetylase activity

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

F

From MGI

GO:0004407

histone deacetylase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

F

From MGI

GO:0005080

protein kinase C binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

F

From MGI

GO:0005515

protein binding

MGI:MGI:2136109
PMID:11390982[2]

IPI: Inferred from Physical Interaction

UniProtKB:O88712

F

From MGI

GO:0005515

protein binding

MGI:MGI:3688344
PMID:15102471[5]

IPI: Inferred from Physical Interaction

UniProtKB:P60335

F

From MGI

GO:0005634

nucleus

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006954

inflammatory response

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007399

nervous system development

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007507

heart development

MGI:MGI:3055619
PMID:15367668[6]

IGI: Inferred from Genetic Interaction

MGI:MGI:1333784

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

F

From MGI

GO:0008134

transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

F

From MGI

GO:0016568

chromatin modification

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0016575

histone deacetylation

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

P

From MGI

GO:0016575

histone deacetylation

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0016575

histone deacetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0030183

B cell differentiation

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0031078

histone deacetylase activity (H3-K14 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032041

NAD-dependent histone deacetylase activity (H3-K14 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032129

histone deacetylase activity (H3-K9 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032869

cellular response to insulin stimulus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

P

From MGI

GO:0033558

protein deacetylase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

F

From MGI

GO:0034739

histone deacetylase activity (H4-K16 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0034983

peptidyl-lysine deacetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

P

From MGI

GO:0035097

histone methyltransferase complex

MGI:MGI:4359370
PMID:12242305[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042113

B cell activation

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0042826

histone deacetylase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

F

From MGI

GO:0045843

negative regulation of striated muscle tissue development

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:1931108
PMID:11022042[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:3607445
PMID:16260608[8]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

P

From MGI

GO:0046969

NAD-dependent histone deacetylase activity (H3-K9 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0046970

NAD-dependent histone deacetylase activity (H4-K16 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0048742

regulation of skeletal muscle fiber development

MGI:MGI:3763703
PMID:17786239[9]

IGI: Inferred from Genetic Interaction

MGI:MGI:1333784
MGI:MGI:3036284

P

From MGI

GO:0051153

regulation of striated muscle cell differentiation

MGI:MGI:3763703
PMID:17786239[9]

IGI: Inferred from Genetic Interaction

MGI:MGI:1333784
MGI:MGI:3036284

P

From MGI

GO:0070491

repressing transcription factor binding

MGI:MGI:4359370
PMID:12242305[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q61686

F

From MGI

GO:0070491

repressing transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

F

From MGI

GO:0070932

histone H3 deacetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

P

From MGI

GO:0070933

histone H4 deacetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

P

From MGI

GO:0090050

positive regulation of cell migration involved in sprouting angiogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UKV0

P

From MGI

NOT

GO:0004407

histone deacetylase activity

MGI:MGI:2136109
PMID:11390982[2]

TAS: Traceable Author Statement

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 Verdin E et al. (2003) Class II histone deacetylases: versatile regulators. Trends Genet 19: 286-93 PubMed GONUTS page
  2. 2.0 2.1 2.2 Zhang CL et al. (2001) The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis. Proc Natl Acad Sci U S A 98: 7354-9 PubMed GONUTS page
  3. Shang L & Tomasi TB (2006) The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons. J Biol Chem 281: 1876-84 PubMed GONUTS page
  4. 4.0 4.1 Zhang CL et al. (2001) Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor. J Biol Chem 276: 35-9 PubMed GONUTS page
  5. Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
  6. Chang S et al. (2004) Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development. Mol Cell Biol 24: 8467-76 PubMed GONUTS page
  7. 7.0 7.1 Zhang CL et al. (2002) Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation. Mol Cell Biol 22: 7302-12 PubMed GONUTS page
  8. Dai YS et al. (2005) The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment. Mol Cell Biol 25: 9936-48 PubMed GONUTS page
  9. 9.0 9.1 Potthoff MJ et al. (2007) Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. J Clin Invest 117: 2459-67 PubMed GONUTS page
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