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MGI:Hdac7

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hdac7 ( synonyms: Hdac7a )
Protein Name(s) histone deacetylase 7,
External Links
MGI MGI:1891835

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000118

histone deacetylase complex

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

C

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:1889866
PMID:10640276[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0001570

vasculogenesis

MGI:MGI:3692697
PMID:16873063[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3693627

P

From MGI

GO:0003682

chromatin binding

MGI:MGI:3611093
PMID:16109736[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003714

transcription corepressor activity

MGI:MGI:1889866
PMID:10640276[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004407

histone deacetylase activity

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005080

protein kinase C binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

F

From MGI

GO:0005515

protein binding

MGI:MGI:1889866
PMID:10640276[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9WU42
UniProtKB:Q60520

F

From MGI

GO:0005515

protein binding

MGI:MGI:3607445
PMID:16260608[5]

IPI: Inferred from Physical Interaction

UniProtKB:O54946

F

From MGI

GO:0005634

nucleus

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:C9JEB6

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006954

inflammatory response

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007043

cell-cell junction assembly

MGI:MGI:3692697
PMID:16873063[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3693627

P

From MGI

GO:0007399

nervous system development

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

F

From MGI

GO:0016568

chromatin modification

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0016575

histone deacetylation

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

P

From MGI

GO:0016575

histone deacetylation

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0019901

protein kinase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

F

From MGI

GO:0030183

B cell differentiation

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0031078

histone deacetylase activity (H3-K14 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032041

NAD-dependent histone deacetylase activity (H3-K14 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032129

histone deacetylase activity (H3-K9 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032703

negative regulation of interleukin-2 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

P

From MGI

GO:0033613

activating transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

F

From MGI

GO:0034739

histone deacetylase activity (H4-K16 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0042113

B cell activation

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0045668

negative regulation of osteoblast differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

P

From MGI

GO:0045843

negative regulation of striated muscle tissue development

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:3607445
PMID:16260608[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:3687879
PMID:12711221[1]

TAS: Traceable Author Statement

P

From MGI

GO:0046969

NAD-dependent histone deacetylase activity (H3-K9 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0046970

NAD-dependent histone deacetylase activity (H4-K16 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0070491

repressing transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

F

From MGI

GO:0071889

14-3-3 protein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

F

From MGI

GO:0090050

positive regulation of cell migration involved in sprouting angiogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WUI4

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 Verdin E et al. (2003) Class II histone deacetylases: versatile regulators. Trends Genet 19: 286-93 PubMed GONUTS page
  2. 2.0 2.1 2.2 Kao HY et al. (2000) Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes Dev 14: 55-66 PubMed GONUTS page
  3. 3.0 3.1 Chang S et al. (2006) Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell 126: 321-34 PubMed GONUTS page
  4. Winnay JN & Hammer GD (2006) Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation. Mol Endocrinol 20: 147-66 PubMed GONUTS page
  5. 5.0 5.1 Dai YS et al. (2005) The DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitment. Mol Cell Biol 25: 9936-48 PubMed GONUTS page
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