Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Hdac1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hdac1 ( synonyms: HD1, MommeD5, RPD3 )
Protein Name(s) histone deacetylase 1,
External Links
MGI MGI:108086

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000118

histone deacetylase complex

MGI:MGI:2683041
PMID:14645126[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q80TZ9

C

From MGI

GO:0000118

histone deacetylase complex

MGI:MGI:3687879
PMID:12711221[2]

TAS: Traceable Author Statement

C

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:1095638
PMID:9271381[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:83998
PMID:8917507[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000785

chromatin

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

C

From MGI

GO:0000790

nuclear chromatin

MGI:MGI:4889029
PMID:21093383[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000792

heterochromatin

MGI:MGI:2682084
PMID:14519686[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000792

heterochromatin

MGI:MGI:2682503
PMID:14643676[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0001047

core promoter binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

F

From MGI

GO:0001103

RNA polymerase II repressing transcription factor binding

MGI:MGI:3837061
PMID:19235719[8]

IPI: Inferred from Physical Interaction

UniProtKB:Q8BIA3

F

From MGI

GO:0001106

RNA polymerase II transcription corepressor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2679393
PMID:14593184[9]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003677

DNA binding

MGI:MGI:3530434
PMID:15608638[10]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003682

chromatin binding

MGI:MGI:3611093
PMID:16109736[11]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003682

chromatin binding

MGI:MGI:3690195
PMID:16678101[12]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003682

chromatin binding

MGI:MGI:3770601
PMID:17905753[13]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:3710033
PMID:17392792[14]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003714

transcription corepressor activity

MGI:MGI:3513590
PMID:15509593[15]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003714

transcription corepressor activity

MGI:MGI:83998
PMID:8917507[5]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004407

histone deacetylase activity

MGI:MGI:3687778
PMID:10615135[16]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004407

histone deacetylase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

F

From MGI

GO:0004407

histone deacetylase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

F

From MGI

GO:0005515

protein binding

MGI:MGI:2152471
PMID:11641275[17]

IPI: Inferred from Physical Interaction

UniProtKB:Q61645

F

From MGI

GO:0005515

protein binding

MGI:MGI:2178733
PMID:11836251[18]

IPI: Inferred from Physical Interaction

UniProtKB:Q9R190
UniProtKB:Q8K4B0
UniProtKB:Q60973
UniProtKB:Q9ER74
UniProtKB:Q9R190

F

From MGI

GO:0005515

protein binding

MGI:MGI:2449749
PMID:12529400[19]

IPI: Inferred from Physical Interaction

UniProtKB:O35613

F

From MGI

GO:0005515

protein binding

MGI:MGI:2668801
PMID:12900441[20]

IPI: Inferred from Physical Interaction

UniProtKB:P97462
UniProtKB:Q61188

F

From MGI

GO:0005515

protein binding

MGI:MGI:2683041
PMID:14645126[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9R190
UniProtKB:O09106
UniProtKB:Q80TZ9

F

From MGI

GO:0005515

protein binding

MGI:MGI:3513590
PMID:15509593[15]

IPI: Inferred from Physical Interaction

UniProtKB:P27889

F

From MGI

GO:0005515

protein binding

MGI:MGI:3587127
PMID:16085498[21]

IPI: Inferred from Physical Interaction

UniProtKB:Q91YE5

F

From MGI

GO:0005515

protein binding

MGI:MGI:3611093
PMID:16109736[11]

IPI: Inferred from Physical Interaction

UniProtKB:P63087
UniProtKB:P63330

F

From MGI

GO:0005515

protein binding

MGI:MGI:3611111
PMID:16103876[22]

IPI: Inferred from Physical Interaction

UniProtKB:O08789
UniProtKB:Q62141

F

From MGI

GO:0005515

protein binding

MGI:MGI:3619832
PMID:16462733[23]

IPI: Inferred from Physical Interaction

UniProtKB:Q8K4B0
UniProtKB:Q9R190
UniProtKB:Q9Z2D8

F

From MGI

GO:0005515

protein binding

MGI:MGI:3687778
PMID:10615135[16]

IPI: Inferred from Physical Interaction

UniProtKB:P13864

F

From MGI

GO:0005515

protein binding

MGI:MGI:3687926
PMID:11931769[24]

IPI: Inferred from Physical Interaction

UniProtKB:P25799
UniProtKB:Q04207

F

From MGI

GO:0005515

protein binding

MGI:MGI:3688346
PMID:15337766[25]

IPI: Inferred from Physical Interaction

UniProtKB:O88939

F

From MGI

GO:0005515

protein binding

MGI:MGI:3716271
PMID:17568773[26]

IPI: Inferred from Physical Interaction

UniProtKB:Q02591

F

From MGI

GO:0005515

protein binding

MGI:MGI:3775414
PMID:11115394[27]

IPI: Inferred from Physical Interaction

UniProtKB:P37094

F

From MGI

GO:0005515

protein binding

MGI:MGI:3830409
PMID:19144721[28]

IPI: Inferred from Physical Interaction

UniProtKB:Q06219

F

From MGI

GO:0005515

protein binding

MGI:MGI:3852313
PMID:12198165[29]

IPI: Inferred from Physical Interaction

UniProtKB:Q91YE5

F

From MGI

GO:0005515

protein binding

MGI:MGI:4359141
PMID:19503085[30]

IPI: Inferred from Physical Interaction

UniProtKB:Q924A0

F

From MGI

GO:0005515

protein binding

MGI:MGI:4367296
PMID:19796622[31]

IPI: Inferred from Physical Interaction

UniProtKB:Q05DS1UniProtKB:Q8BX22

F

From MGI

GO:0005515

protein binding

MGI:MGI:4943402
PMID:16805913[32]

IPI: Inferred from Physical Interaction

UniProtKB:Q8R5A0

F

From MGI

GO:0005515

protein binding

MGI:MGI:5294529
PMID:20599664[33]

IPI: Inferred from Physical Interaction

UniProtKB:Q15327

F

From MGI

GO:0005515

protein binding

MGI:MGI:83998
PMID:8917507[5]

IPI: Inferred from Physical Interaction

UniProtKB:P25490

F

From MGI

GO:0005515

protein binding

MGI:MGI:87394
PMID:9139821[34]

IPI: Inferred from Physical Interaction

UniProtKB:Q62141-1

F

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:F5GXM1

C

From MGI

GO:0005634

nucleus

MGI:MGI:5291872
PMID:21874024[35]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:3719935
PMID:17182846[36]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QYB2
UniProtKB:P70288
UniProtKB:Q60520
UniProtKB:Q60974
UniProtKB:P05627

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:5284774
PMID:17707228[37]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3687879
PMID:12711221[2]

TAS: Traceable Author Statement

C

From MGI

GO:0005829

cytosol

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006476

protein deacetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0007492

endoderm development

MGI:MGI:3041938
PMID:15060137[38]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007492

endoderm development

MGI:MGI:3041938
PMID:15060137[38]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:3687879
PMID:12711221[2]

TAS: Traceable Author Statement

F

From MGI

GO:0008134

transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

F

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

P

From MGI

GO:0009913

epidermal cell differentiation

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0010870

positive regulation of receptor biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0016568

chromatin modification

MGI:MGI:3687879
PMID:12711221[2]

TAS: Traceable Author Statement

P

From MGI

GO:0016575

histone deacetylation

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

P

From MGI

GO:0016575

histone deacetylation

MGI:MGI:3687778
PMID:10615135[16]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016575

histone deacetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0016580

Sin3 complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

C

From MGI

GO:0016581

NuRD complex

MGI:MGI:2178733
PMID:11836251[18]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016581

NuRD complex

MGI:MGI:2683041
PMID:14645126[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9R190

C

From MGI

GO:0016581

NuRD complex

MGI:MGI:3619832
PMID:16462733[23]

IPI: Inferred from Physical Interaction

UniProtKB:Q8K4B0
UniProtKB:Q9R190
UniProtKB:Q9Z2D8

C

From MGI

GO:0016581

NuRD complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

C

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0017053

transcriptional repressor complex

MGI:MGI:3719935
PMID:17182846[36]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QYB2
UniProtKB:P70288
UniProtKB:Q60520
UniProtKB:Q60974
UniProtKB:P05627

C

From MGI

GO:0019899

enzyme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

F

From MGI

GO:0021766

hippocampus development

MGI:MGI:3844761
PMID:19380719[39]

IGI: Inferred from Genetic Interaction

MGI:MGI:1097691

P

From MGI

GO:0030182

neuron differentiation

MGI:MGI:3844761
PMID:19380719[39]

IGI: Inferred from Genetic Interaction

MGI:MGI:1097691

P

From MGI

GO:0031078

histone deacetylase activity (H3-K14 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032041

NAD-dependent histone deacetylase activity (H3-K14 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032129

histone deacetylase activity (H3-K9 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0032403

protein complex binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

F

From MGI

GO:0033558

protein deacetylase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

F

From MGI

GO:0033613

activating transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

F

From MGI

GO:0034599

cellular response to oxidative stress

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

P

From MGI

GO:0034739

histone deacetylase activity (H4-K16 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0042475

odontogenesis of dentin-containing tooth

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0042733

embryonic digit morphogenesis

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0042826

histone deacetylase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

F

From MGI

GO:0043025

neuronal cell body

MGI:MGI:3807105
PMID:18651664[40]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0043234

protein complex

MGI:MGI:4367296
PMID:19796622[31]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043234

protein complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

C

From MGI

GO:0043524

negative regulation of neuron apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

P

From MGI

GO:0043922

negative regulation by host of viral transcription

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:1095638
PMID:9271381[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0046969

NAD-dependent histone deacetylase activity (H3-K9 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0046970

NAD-dependent histone deacetylase activity (H4-K16 specific)

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.5.1.98

F

From MGI

GO:0048714

positive regulation of oligodendrocyte differentiation

MGI:MGI:4359141
PMID:19503085[30]

IGI: Inferred from Genetic Interaction

MGI:MGI:1097691

P

From MGI

GO:0060766

negative regulation of androgen receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0060789

hair follicle placode formation

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0061029

eyelid development in camera-type eye

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0061198

fungiform papilla formation

MGI:MGI:4889029
PMID:21093383[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70288

P

From MGI

GO:0070932

histone H3 deacetylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001020580

P

From MGI

GO:0070932

histone H3 deacetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0070933

histone H4 deacetylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13547

P

From MGI

GO:0090090

negative regulation of canonical Wnt receptor signaling pathway

MGI:MGI:4359141
PMID:19503085[30]

IGI: Inferred from Genetic Interaction

MGI:MGI:1097691

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. ↑ 1.0 1.1 1.2 Zoltewicz JS et al. (2004) Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development 131: 3-14 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 Verdin E et al. (2003) Class II histone deacetylases: versatile regulators. Trends Genet 19: 286-93 PubMed GONUTS page
  3. ↑ 3.0 3.1 Bartl S et al. (1997) Identification of mouse histone deacetylase 1 as a growth factor-inducible gene. Mol Cell Biol 17: 5033-43 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 LeBoeuf M et al. (2010) Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell 19: 807-18 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 Yang WM et al. (1996) Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc Natl Acad Sci U S A 93: 12845-50 PubMed GONUTS page
  6. ↑ Craig JM et al. (2003) Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet 12: 3109-21 PubMed GONUTS page
  7. ↑ Kantor B et al. (2003) Expression and localization of components of the histone deacetylases multiprotein repressory complexes in the mouse preimplantation embryo. Gene Expr Patterns 3: 697-702 PubMed GONUTS page
  8. ↑ Anderson DM et al. (2009) The homeobox gene Mohawk represses transcription by recruiting the sin3A/HDAC co-repressor complex. Dev Dyn 238: 572-80 PubMed GONUTS page
  9. ↑ Martinowich K et al. (2003) DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 302: 890-3 PubMed GONUTS page
  10. ↑ Horike S et al. (2005) Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet 37: 31-40 PubMed GONUTS page
  11. ↑ 11.0 11.1 Winnay JN & Hammer GD (2006) Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation. Mol Endocrinol 20: 147-66 PubMed GONUTS page
  12. ↑ Olson LE et al. (2006) Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell 125: 593-605 PubMed GONUTS page
  13. ↑ Pérez-Mancera PA et al. (2007) Adipose tissue mass is modulated by SLUG (SNAI2). Hum Mol Genet 16: 2972-86 PubMed GONUTS page
  14. ↑ Wang J et al. (2007) Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 446: 882-7 PubMed GONUTS page
  15. ↑ 15.0 15.1 Barbacci E et al. (2004) HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment. Hum Mol Genet 13: 3139-49 PubMed GONUTS page
  16. ↑ 16.0 16.1 16.2 Fuks F et al. (2000) DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet 24: 88-91 PubMed GONUTS page
  17. ↑ Potter GB et al. (2001) The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor. Genes Dev 15: 2687-701 PubMed GONUTS page
  18. ↑ 18.0 18.1 Kiefer SM et al. (2002) Murine Sall1 represses transcription by recruiting a histone deacetylase complex. J Biol Chem 277: 14869-76 PubMed GONUTS page
  19. ↑ Ecsedy JA et al. (2003) Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity. Mol Cell Biol 23: 950-60 PubMed GONUTS page
  20. ↑ Erhardt S et al. (2003) Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development 130: 4235-48 PubMed GONUTS page
  21. ↑ Zhou Y & Grummt I (2005) The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing. Curr Biol 15: 1434-8 PubMed GONUTS page
  22. ↑ Popov N et al. (2005) Mnt transcriptional repressor is functionally regulated during cell cycle progression. Oncogene 24: 8326-37 PubMed GONUTS page
  23. ↑ 23.0 23.1 Kaji K et al. (2006) The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol 8: 285-92 PubMed GONUTS page
  24. ↑ Zhong H et al. (2002) The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell 9: 625-36 PubMed GONUTS page
  25. ↑ Liu CJ et al. (2004) Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. J Biol Chem 279: 47081-91 PubMed GONUTS page
  26. ↑ Izzi L et al. (2007) Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development. EMBO J 26: 3132-43 PubMed GONUTS page
  27. ↑ Mehra-Chaudhary R et al. (2001) Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter. Biochem J 353: 13-22 PubMed GONUTS page
  28. ↑ Jacobs FM et al. (2009) Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression. Development 136: 531-40 PubMed GONUTS page
  29. ↑ Zhou Y et al. (2002) The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J 21: 4632-40 PubMed GONUTS page
  30. ↑ 30.0 30.1 30.2 Ye F et al. (2009) HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci 12: 829-38 PubMed GONUTS page
  31. ↑ 31.0 31.1 Nishiyama A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5: 420-33 PubMed GONUTS page
  32. ↑ Brown MA et al. (2006) Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex. Mol Cancer 5: 26 PubMed GONUTS page
  33. ↑ Kojic S et al. (2010) A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein. Arch Biochem Biophys 502: 60-7 PubMed GONUTS page
  34. ↑ Alland L et al. (1997) Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 387: 49-55 PubMed GONUTS page
  35. ↑ Chang M et al. (2011) The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity. Nat Immunol 12: 1002-9 PubMed GONUTS page
  36. ↑ 36.0 36.1 Wu K et al. (2007) Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Mol Biol Cell 18: 755-67 PubMed GONUTS page
  37. ↑ Saleque S et al. (2007) Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1. Mol Cell 27: 562-72 PubMed GONUTS page
  38. ↑ 38.0 38.1 Tou L et al. (2004) Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases. Mol Cell Biol 24: 3132-9 PubMed GONUTS page
  39. ↑ 39.0 39.1 Montgomery RL et al. (2009) Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc Natl Acad Sci U S A 106: 7876-81 PubMed GONUTS page
  40. ↑ MacDonald JL & Roskams AJ (2008) Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development. Dev Dyn 237: 2256-67 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox