![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Hdac1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hdac1 ( synonyms: HD1, MommeD5, RPD3 ) | |
| Protein Name(s) | histone deacetylase 1, | |
| External Links | ||
| MGI | MGI:108086 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000118 |
histone deacetylase complex |
MGI:MGI:2683041 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0000118 |
histone deacetylase complex |
MGI:MGI:3687879 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:1095638 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:83998 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000785 |
chromatin |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
C |
From MGI |
||
| GO:0000790 |
nuclear chromatin |
MGI:MGI:4889029 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:2682084 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:2682503 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001047 |
core promoter binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001103 |
RNA polymerase II repressing transcription factor binding |
MGI:MGI:3837061 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0001106 |
RNA polymerase II transcription corepressor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:2679393 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:3530434 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:3611093 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:3690195 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:3770601 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:3710033 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:3513590 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:83998 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004407 |
histone deacetylase activity |
MGI:MGI:3687778 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004407 |
histone deacetylase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
F |
From MGI |
||
| GO:0004407 |
histone deacetylase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2152471 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2178733 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q9R190 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:2449749 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2668801 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2683041 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3513590 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3587127 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3611093 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3611111 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3619832 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3687778 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3687926 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3688346 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3716271 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3775414 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3830409 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3852313 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4359141 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4367296 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q05DS1UniProtKB:Q8BX22 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:4943402 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5294529 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:83998 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:87394 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:5291872 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:3719935 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q9QYB2 |
C |
From MGI |
||
| GO:0005667 |
transcription factor complex |
MGI:MGI:5284774 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3687879 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006476 |
protein deacetylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007492 |
endoderm development |
MGI:MGI:3041938 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007492 |
endoderm development |
MGI:MGI:3041938 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:3687879 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
P |
From MGI |
||
| GO:0009913 |
epidermal cell differentiation |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0010870 |
positive regulation of receptor biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016568 |
chromatin modification |
MGI:MGI:3687879 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0016575 |
histone deacetylation |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016575 |
histone deacetylation |
MGI:MGI:3687778 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016575 |
histone deacetylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016580 |
Sin3 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016581 |
NuRD complex |
MGI:MGI:2178733 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016581 |
NuRD complex |
MGI:MGI:2683041 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0016581 |
NuRD complex |
MGI:MGI:3619832 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0016581 |
NuRD complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0017053 |
transcriptional repressor complex |
MGI:MGI:3719935 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q9QYB2 |
C |
From MGI |
||
| GO:0019899 |
enzyme binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0021766 |
hippocampus development |
MGI:MGI:3844761 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097691 |
P |
From MGI |
||
| GO:0030182 |
neuron differentiation |
MGI:MGI:3844761 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097691 |
P |
From MGI |
||
| GO:0031078 |
histone deacetylase activity (H3-K14 specific) |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0032041 |
NAD-dependent histone deacetylase activity (H3-K14 specific) |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0032129 |
histone deacetylase activity (H3-K9 specific) |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
F |
From MGI |
||
| GO:0033558 |
protein deacetylase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0033613 |
activating transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0034599 |
cellular response to oxidative stress |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
P |
From MGI |
||
| GO:0034739 |
histone deacetylase activity (H4-K16 specific) |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0042475 |
odontogenesis of dentin-containing tooth |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0042733 |
embryonic digit morphogenesis |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0042826 |
histone deacetylase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043025 |
neuronal cell body |
MGI:MGI:3807105 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4367296 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
C |
From MGI |
||
| GO:0043524 |
negative regulation of neuron apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
P |
From MGI |
||
| GO:0043922 |
negative regulation by host of viral transcription |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:1095638 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
P |
From MGI |
||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046969 |
NAD-dependent histone deacetylase activity (H3-K9 specific) |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0046970 |
NAD-dependent histone deacetylase activity (H4-K16 specific) |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0048714 |
positive regulation of oligodendrocyte differentiation |
MGI:MGI:4359141 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097691 |
P |
From MGI |
||
| GO:0060766 |
negative regulation of androgen receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060789 |
hair follicle placode formation |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0061029 |
eyelid development in camera-type eye |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0061198 |
fungiform papilla formation |
MGI:MGI:4889029 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0070932 |
histone H3 deacetylation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001020580 |
P |
From MGI |
||
| GO:0070932 |
histone H3 deacetylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070933 |
histone H4 deacetylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:4359141 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097691 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Zoltewicz JS et al. (2004) Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development 131: 3-14 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Verdin E et al. (2003) Class II histone deacetylases: versatile regulators. Trends Genet 19: 286-93 PubMed GONUTS page
- ↑ 3.0 3.1 Bartl S et al. (1997) Identification of mouse histone deacetylase 1 as a growth factor-inducible gene. Mol Cell Biol 17: 5033-43 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 LeBoeuf M et al. (2010) Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell 19: 807-18 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Yang WM et al. (1996) Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc Natl Acad Sci U S A 93: 12845-50 PubMed GONUTS page
- ↑ Craig JM et al. (2003) Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet 12: 3109-21 PubMed GONUTS page
- ↑ Kantor B et al. (2003) Expression and localization of components of the histone deacetylases multiprotein repressory complexes in the mouse preimplantation embryo. Gene Expr Patterns 3: 697-702 PubMed GONUTS page
- ↑ Anderson DM et al. (2009) The homeobox gene Mohawk represses transcription by recruiting the sin3A/HDAC co-repressor complex. Dev Dyn 238: 572-80 PubMed GONUTS page
- ↑ Martinowich K et al. (2003) DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 302: 890-3 PubMed GONUTS page
- ↑ Horike S et al. (2005) Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet 37: 31-40 PubMed GONUTS page
- ↑ 11.0 11.1 Winnay JN & Hammer GD (2006) Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation. Mol Endocrinol 20: 147-66 PubMed GONUTS page
- ↑ Olson LE et al. (2006) Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell 125: 593-605 PubMed GONUTS page
- ↑ Pérez-Mancera PA et al. (2007) Adipose tissue mass is modulated by SLUG (SNAI2). Hum Mol Genet 16: 2972-86 PubMed GONUTS page
- ↑ Wang J et al. (2007) Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 446: 882-7 PubMed GONUTS page
- ↑ 15.0 15.1 Barbacci E et al. (2004) HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment. Hum Mol Genet 13: 3139-49 PubMed GONUTS page
- ↑ 16.0 16.1 16.2 Fuks F et al. (2000) DNA methyltransferase Dnmt1 associates with histone deacetylase activity. Nat Genet 24: 88-91 PubMed GONUTS page
- ↑ Potter GB et al. (2001) The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor. Genes Dev 15: 2687-701 PubMed GONUTS page
- ↑ 18.0 18.1 Kiefer SM et al. (2002) Murine Sall1 represses transcription by recruiting a histone deacetylase complex. J Biol Chem 277: 14869-76 PubMed GONUTS page
- ↑ Ecsedy JA et al. (2003) Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity. Mol Cell Biol 23: 950-60 PubMed GONUTS page
- ↑ Erhardt S et al. (2003) Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development 130: 4235-48 PubMed GONUTS page
- ↑ Zhou Y & Grummt I (2005) The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing. Curr Biol 15: 1434-8 PubMed GONUTS page
- ↑ Popov N et al. (2005) Mnt transcriptional repressor is functionally regulated during cell cycle progression. Oncogene 24: 8326-37 PubMed GONUTS page
- ↑ 23.0 23.1 Kaji K et al. (2006) The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol 8: 285-92 PubMed GONUTS page
- ↑ Zhong H et al. (2002) The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell 9: 625-36 PubMed GONUTS page
- ↑ Liu CJ et al. (2004) Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. J Biol Chem 279: 47081-91 PubMed GONUTS page
- ↑ Izzi L et al. (2007) Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development. EMBO J 26: 3132-43 PubMed GONUTS page
- ↑ Mehra-Chaudhary R et al. (2001) Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter. Biochem J 353: 13-22 PubMed GONUTS page
- ↑ Jacobs FM et al. (2009) Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression. Development 136: 531-40 PubMed GONUTS page
- ↑ Zhou Y et al. (2002) The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J 21: 4632-40 PubMed GONUTS page
- ↑ 30.0 30.1 30.2 Ye F et al. (2009) HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci 12: 829-38 PubMed GONUTS page
- ↑ 31.0 31.1 Nishiyama A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5: 420-33 PubMed GONUTS page
- ↑ Brown MA et al. (2006) Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex. Mol Cancer 5: 26 PubMed GONUTS page
- ↑ Kojic S et al. (2010) A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein. Arch Biochem Biophys 502: 60-7 PubMed GONUTS page
- ↑ Alland L et al. (1997) Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 387: 49-55 PubMed GONUTS page
- ↑ Chang M et al. (2011) The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity. Nat Immunol 12: 1002-9 PubMed GONUTS page
- ↑ 36.0 36.1 Wu K et al. (2007) Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Mol Biol Cell 18: 755-67 PubMed GONUTS page
- ↑ Saleque S et al. (2007) Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1. Mol Cell 27: 562-72 PubMed GONUTS page
- ↑ 38.0 38.1 Tou L et al. (2004) Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases. Mol Cell Biol 24: 3132-9 PubMed GONUTS page
- ↑ 39.0 39.1 Montgomery RL et al. (2009) Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc Natl Acad Sci U S A 106: 7876-81 PubMed GONUTS page
- ↑ MacDonald JL & Roskams AJ (2008) Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development. Dev Dyn 237: 2256-67 PubMed GONUTS page