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MGI:Hd

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Mus musculus (house mouse)

Hd:Huntington disease (human)
Synonyms:HD, Hdh, htt, huntingtin, IT15
Hd on MGI

GO terms

GO:0005515_!_protein_binding (F) ISS with/from UniProt:Q9UQB7 [1]
GO:0005515_!_protein_binding (F) IPI with/from UniProt:O35668,UniProt:O08788 [2]
GO:0005634_!_nucleus (C) IEA with/from SP_KW:KW-0539 [3]
GO:0005634_!_nucleus (C) IEA with/from InterPro:IPR000091 [4]
GO:0005737_!_cytoplasm (C) IEA with/from SP_KW:KW-0963 [3]
GO:0005737_!_cytoplasm (C) IEA with/from InterPro:IPR000091 [4]
GO:0006916_!_anti-apoptosis (P) IDA [2]
GO:0009653_!_anatomical_structure_morphogenesis (P) IMP with/from MGI:MGI:1857180 [5]
GO:0009952_!_anterior/posterior_pattern_formation (P) IMP with/from MGI:MGI:1857180 [5]
GO:0016023_!_cytoplasmic_membrane-bound_vesicle (C) IDA [2]
GO:0016234_!_inclusion_body (C) IDA [6]
GO:0047496_!_vesicle_transport_along_microtubule (P) IDA [2]
GO:0048341_!_paraxial_mesoderm_formation (P) IMP with/from MGI:MGI:1857180 [5]

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Notes

References

See Help:References for how to manage references in GONUTS.
  1. Gervais FG et al. (2002) Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat Cell Biol 4: 95-105 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gauthier LR et al. (2004) Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118: 127-38 PubMed GONUTS page
  3. 3.0 3.1 MGI annotation MGI:1354194
  4. 4.0 4.1 MGI annotation MGI:2152098
  5. 5.0 5.1 5.2 Woda JM et al. (2005) Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo. BMC Dev Biol 5: 17 PubMed GONUTS page
  6. Irwin S et al. (2005) RNA association and nucleocytoplasmic shuttling by ataxin-1. J Cell Sci 118: 233-42 PubMed GONUTS page
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