![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Hcls1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hcls1 ( synonyms: HS1 ) | |
| Protein Name(s) | hematopoietic cell specific Lyn substrate 1, | |
| External Links | ||
| MGI | MGI:104568 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
MGI:MGI:3694161 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3694161 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3694161 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0496 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:3694161 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009725 |
response to hormone stimulus |
MGI:MGI:3694161 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0017124 |
SH3 domain binding |
MGI:MGI:1326779 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0017124 |
SH3 domain binding |
MGI:MGI:3844204 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0030218 |
erythrocyte differentiation |
MGI:MGI:3694161 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:3844204 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0042531 |
positive regulation of tyrosine phosphorylation of STAT protein |
MGI:MGI:3694161 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Ingley E et al. (2000) HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells. J Biol Chem 275: 7887-93 PubMed GONUTS page
- ↑ Yamabhai M & Kay BK (1997) Examining the specificity of Src homology 3 domain--ligand interactions with alkaline phosphatase fusion proteins. Anal Biochem 247: 143-51 PubMed GONUTS page
- ↑ 3.0 3.1 Samuels AL et al. (2009) Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. Blood 113: 3845-56 PubMed GONUTS page
abcde |
fgmnp |
p cont.
rstv |