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MGI:Hck

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hck ( synonyms: Bmk, Hck-1 )
Protein Name(s) hemopoietic cell kinase,
External Links
MGI MGI:96052

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245

F

From MGI

GO:0004713

protein tyrosine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

F

From MGI

GO:0004715

non-membrane spanning protein tyrosine kinase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.7.10.2

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005764

lysosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0333

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0005901

caveola

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

C

From MGI

GO:0005925

focal adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266
InterPro:IPR020635

P

From MGI

GO:0006887

exocytosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0268

P

From MGI

GO:0006909

phagocytosis

MGI:MGI:65050
PMID:8125254[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2384049

P

From MGI

GO:0006954

inflammatory response

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0395

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI

GO:0008360

regulation of cell shape

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0018108

peptidyl-tyrosine phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI

GO:0030054

cell junction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From MGI

GO:0031234

extrinsic to internal side of plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

C

From MGI

GO:0031410

cytoplasmic vesicle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0968

C

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI

GO:0045087

innate immune response

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0399

P

From MGI

GO:0046777

protein autophosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI

GO:0050764

regulation of phagocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI

GO:0050830

defense response to Gram-positive bacterium

MGI:MGI:65050
PMID:8125254[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:95527

P

From MGI

GO:0051090

regulation of sequence-specific DNA binding transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI

GO:0071801

regulation of podosome assembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI

GO:2000251

positive regulation of actin cytoskeleton reorganization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P08631

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Lowell CA et al. (1994) Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity. Genes Dev 8: 387-98 PubMed GONUTS page
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