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MGI:Hap1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Hap1 ( synonyms: HAP-1 )
Protein Name(s) huntingtin-associated protein 1,
External Links
MGI MGI:1261831

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

MGI:MGI:1206607
PMID:9599014[1]

IPI: Inferred from Physical Interaction

UniProtKB:P42859

F

From MGI

GO:0005515

protein binding

MGI:MGI:3046393
PMID:15242649[2]

IPI: Inferred from Physical Interaction

UniProtKB:P42859
UniProtKB:O08788

F

From MGI

GO:0005515

protein binding

MGI:MGI:5284788
PMID:16339760[3]

IPI: Inferred from Physical Interaction

UniProtKB:B2GV74

F

From MGI

GO:0005622

intracellular

MGI:MGI:3046393
PMID:15242649[2]

IMP: Inferred from Mutant Phenotype

C

From MGI

GO:0008104

protein localization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P54257

P

From MGI

GO:0010976

positive regulation of neuron projection development

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P54256

P

From MGI

GO:0016023

cytoplasmic membrane-bounded vesicle

MGI:MGI:3046393
PMID:15242649[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030425

dendrite

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P54256

C

From MGI

GO:0030426

growth cone

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P54256

C

From MGI

GO:0043005

neuron projection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P54256

C

From MGI

GO:0043679

axon terminus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P54256

C

From MGI

GO:0047496

vesicle transport along microtubule

MGI:MGI:3046393
PMID:15242649[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P54256

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Bertaux F et al. (1998) HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice. FEBS Lett 426: 229-32 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gauthier LR et al. (2004) Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118: 127-38 PubMed GONUTS page
  3. McGuire JR et al. (2006) Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons. J Biol Chem 281: 3552-9 PubMed GONUTS page
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