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MGI:Hadhb
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Hadhb ( synonyms: Mtpb ) | |
| Protein Name(s) | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit, | |
| External Links | ||
| MGI | MGI:2136381 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000062 |
fatty-acyl-CoA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003857 |
3-hydroxyacyl-CoA dehydrogenase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003988 |
acetyl-CoA C-acyltransferase activity |
MGI:MGI:3606365 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003988 |
acetyl-CoA C-acyltransferase activity |
MGI:MGI:3697529 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3698125 |
F |
From MGI |
||
| GO:0003988 |
acetyl-CoA C-acyltransferase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004300 |
enoyl-CoA hydratase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2135592 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2682130 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3697529 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3698125 |
C |
From MGI |
||
| GO:0005739 |
mitochondrion |
MGI:MGI:3852644 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005743 |
mitochondrial inner membrane |
MGI:MGI:3590069 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0443 |
P |
From MGI |
||
| GO:0006631 |
fatty acid metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0276 |
P |
From MGI |
||
| GO:0006635 |
fatty acid beta-oxidation |
MGI:MGI:2135592 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006635 |
fatty acid beta-oxidation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016507 |
mitochondrial fatty acid beta-oxidation multienzyme complex |
MGI:MGI:3697529 |
IC: Inferred by Curator |
GO:0003988 GO:0016509 |
C |
From MGI |
||
| GO:0016507 |
mitochondrial fatty acid beta-oxidation multienzyme complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016508 |
long-chain-enoyl-CoA hydratase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016509 |
long-chain-3-hydroxyacyl-CoA dehydrogenase activity |
MGI:MGI:3697529 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3698125 |
F |
From MGI |
||
| GO:0016509 |
long-chain-3-hydroxyacyl-CoA dehydrogenase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016746 |
transferase activity, transferring acyl groups |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0012 |
F |
From MGI |
||
| GO:0016747 |
transferase activity, transferring acyl groups other than amino-acyl groups |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002155 |
F |
From MGI |
||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042645 |
mitochondrial nucleoid |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0051287 |
NAD binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Shekhawat PS et al. (2004) Carnitine content and expression of mitochondrial beta-oxidation enzymes in placentas of wild-type (OCTN2(+/+)) and OCTN2 Null (OCTN2(-/-)) Mice. Pediatr Res 56: 323-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Kao HJ et al. (2006) ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit. Hum Mol Genet 15: 3569-77 PubMed GONUTS page
- ↑ 3.0 3.1 Ibdah JA et al. (2001) Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death. J Clin Invest 107: 1403-9 PubMed GONUTS page
- ↑ Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
- ↑ Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
- ↑ Da Cruz S et al. (2003) Proteomic analysis of the mouse liver mitochondrial inner membrane. J Biol Chem 278: 41566-71 PubMed GONUTS page
