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MGI:H2-DMb2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) H2-DMb2 ( synonyms: H-2Mb2, H2-M beta2, H2-Mb2 )
Protein Name(s) histocompatibility 2, class II, locus Mb2,
External Links
MGI MGI:95923

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002504

antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0491

P

From MGI

GO:0005515

protein binding

MGI:MGI:1290041
PMID:9768758[1]

IPI: Inferred from Physical Interaction

UniProtKB:P28078

F

From MGI

GO:0005764

lysosome

MGI:MGI:3033879
PMID:11854359[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005765

lysosomal membrane

MGI:MGI:3033877
PMID:7584146[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005770

late endosome

MGI:MGI:3033877
PMID:7584146[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005771

multivesicular body

MGI:MGI:3033879
PMID:11854359[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0010008

endosome membrane

MGI:MGI:3033877
PMID:7584146[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:3033877
PMID:7584146[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019882

antigen processing and presentation

MGI:MGI:1933465
PMID:11148202[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0019882

antigen processing and presentation

MGI:MGI:3033877
PMID:7584146[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0019882

antigen processing and presentation

MGI:MGI:58524
PMID:2508088[5]

ISA: Inferred from Sequence Alignment

EMBL:U38501

P

From MGI

GO:0019886

antigen processing and presentation of exogenous peptide antigen via MHC class II

MGI:MGI:3033882
PMID:11027433[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042613

MHC class II protein complex

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0491

C

From MGI

GO:0051085

chaperone mediated protein folding requiring cofactor

MGI:MGI:1933465
PMID:11148202[4]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Fremont DH et al. (1998) Crystal structure of mouse H2-M. Immunity 9: 385-93 PubMed GONUTS page
  2. 2.0 2.1 Lankar D et al. (2002) Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation. J Exp Med 195: 461-72 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Lindstedt R et al. (1995) The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif. Immunity 3: 561-72 PubMed GONUTS page
  4. 4.0 4.1 Walter W et al. (2001) H2-Mbeta 1 and H2-Mbeta 2 heterodimers equally promote clip removal in I-A(q) molecules from autoimmune-prone DBA/1 mice. J Biol Chem 276: 11086-91 PubMed GONUTS page
  5. Strathmann M et al. (1989) Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Proc Natl Acad Sci U S A 86: 7407-9 PubMed GONUTS page
  6. Walter W et al. (2000) MHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance? Br J Cancer 83: 1192-201 PubMed GONUTS page
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