![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:H2-DMb2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | H2-DMb2 ( synonyms: H-2Mb2, H2-M beta2, H2-Mb2 ) | |
| Protein Name(s) | histocompatibility 2, class II, locus Mb2, | |
| External Links | ||
| MGI | MGI:95923 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002504 |
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0491 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:1290041 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005764 |
lysosome |
MGI:MGI:3033879 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005765 |
lysosomal membrane |
MGI:MGI:3033877 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005770 |
late endosome |
MGI:MGI:3033877 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005771 |
multivesicular body |
MGI:MGI:3033879 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0010008 |
endosome membrane |
MGI:MGI:3033877 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:3033877 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0019882 |
antigen processing and presentation |
MGI:MGI:1933465 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0019882 |
antigen processing and presentation |
MGI:MGI:3033877 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0019882 |
antigen processing and presentation |
MGI:MGI:58524 |
ISA: Inferred from Sequence Alignment |
EMBL:U38501 |
P |
From MGI |
||
| GO:0019886 |
antigen processing and presentation of exogenous peptide antigen via MHC class II |
MGI:MGI:3033882 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042613 |
MHC class II protein complex |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0491 |
C |
From MGI |
||
| GO:0051085 |
chaperone mediated protein folding requiring cofactor |
MGI:MGI:1933465 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Fremont DH et al. (1998) Crystal structure of mouse H2-M. Immunity 9: 385-93 PubMed GONUTS page
- ↑ 2.0 2.1 Lankar D et al. (2002) Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation. J Exp Med 195: 461-72 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Lindstedt R et al. (1995) The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif. Immunity 3: 561-72 PubMed GONUTS page
- ↑ 4.0 4.1 Walter W et al. (2001) H2-Mbeta 1 and H2-Mbeta 2 heterodimers equally promote clip removal in I-A(q) molecules from autoimmune-prone DBA/1 mice. J Biol Chem 276: 11086-91 PubMed GONUTS page
- ↑ Strathmann M et al. (1989) Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Proc Natl Acad Sci U S A 86: 7407-9 PubMed GONUTS page
- ↑ Walter W et al. (2000) MHC class II antigen presentation pathway in murine tumours: tumour evasion from immunosurveillance? Br J Cancer 83: 1192-201 PubMed GONUTS page