Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Gsx2

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Gsx2 ( synonyms: Gsh-2, Gsh2 )
Protein Name(s) GS homeobox 2,
External Links
MGI MGI:95843

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002087

regulation of respiratory gaseous exchange by neurological system process

MGI:MGI:1099899
PMID:9398437[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0003677

DNA binding

MGI:MGI:72159
PMID:7619729[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005634

nucleus

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007389

pattern specification process

MGI:MGI:2153441
PMID:11731457[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0007389

pattern specification process

MGI:MGI:2662646
PMID:12724834[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0007389

pattern specification process

MGI:MGI:2675248
PMID:12930780[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:108067

P

From MGI

GO:0007389

pattern specification process

MGI:MGI:3579956
PMID:15930101[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0007417

central nervous system development

MGI:MGI:2153441
PMID:11731457[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0007417

central nervous system development

MGI:MGI:2662646
PMID:12724834[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0007420

brain development

MGI:MGI:2675248
PMID:12930780[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:108067

P

From MGI

GO:0021527

spinal cord association neuron differentiation

MGI:MGI:3639800
PMID:16715081[7]

IGI: Inferred from Genetic Interaction

MGI:MGI:95842

P

From MGI

GO:0021575

hindbrain morphogenesis

MGI:MGI:1099899
PMID:9398437[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0021798

forebrain dorsal/ventral pattern formation

MGI:MGI:1926244
PMID:11060228[8]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0021798

forebrain dorsal/ventral pattern formation

MGI:MGI:1928687
PMID:11124115[9]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0021889

olfactory bulb interneuron differentiation

MGI:MGI:1926244
PMID:11060228[8]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

F

From MGI

GO:0048663

neuron fate commitment

MGI:MGI:3639800
PMID:16715081[7]

IGI: Inferred from Genetic Interaction

MGI:MGI:95842

P

From MGI

GO:0048665

neuron fate specification

MGI:MGI:3579956
PMID:15930101[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0048853

forebrain morphogenesis

MGI:MGI:1099899
PMID:9398437[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI

GO:0060163

subpallium neuron fate commitment

MGI:MGI:1928687
PMID:11124115[9]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2150162

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Szucsik JC et al. (1997) Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene. Dev Biol 191: 230-42 PubMed GONUTS page
  2. Hsieh-Li HM et al. (1995) Gsh-2, a murine homeobox gene expressed in the developing brain. Mech Dev 50: 177-86 PubMed GONUTS page
  3. 3.0 3.1 Toresson H & Campbell K (2001) A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development 128: 4769-80 PubMed GONUTS page
  4. 4.0 4.1 Yun K et al. (2003) Patterning of the lateral ganglionic eminence by the Gsh1 and Gsh2 homeobox genes regulates striatal and olfactory bulb histogenesis and the growth of axons through the basal ganglia. J Comp Neurol 461: 151-65 PubMed GONUTS page
  5. 5.0 5.1 Corbin JG et al. (2003) Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development 130: 4895-906 PubMed GONUTS page
  6. 6.0 6.1 Kriks S et al. (2005) Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord. Development 132: 2991-3002 PubMed GONUTS page
  7. 7.0 7.1 Mizuguchi R et al. (2006) Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons. Nat Neurosci 9: 770-8 PubMed GONUTS page
  8. 8.0 8.1 Corbin JG et al. (2000) The Gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development 127: 5007-20 PubMed GONUTS page
  9. 9.0 9.1 Yun K et al. (2001) Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon. Development 128: 193-205 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox