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MGI:Gsc
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Gsc | |
| Protein Name(s) | goosecoid homeobox, | |
| External Links | ||
| MGI | MGI:95841 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3716271 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1347465 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3716271 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:3716271 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0009653 |
anatomical structure morphogenesis |
MGI:MGI:894511 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1347476 |
P |
From MGI |
||
| GO:0021904 |
dorsal/ventral neural tube patterning |
MGI:MGI:894511 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1347476 |
P |
From MGI |
||
| GO:0023019 |
signal transduction involved in regulation of gene expression |
MGI:MGI:4415813 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
MGI:MGI:3703477 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857726 |
P |
From MGI |
||
| GO:0030900 |
forebrain development |
MGI:MGI:3703477 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1329040 |
P |
From MGI |
||
| GO:0042474 |
middle ear morphogenesis |
MGI:MGI:3035838 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0043583 |
ear development |
MGI:MGI:76955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857496 |
P |
From MGI |
||
| GO:0048644 |
muscle organ morphogenesis |
MGI:MGI:76955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857496 |
P |
From MGI |
||
| GO:0048704 |
embryonic skeletal system morphogenesis |
MGI:MGI:76246 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857726 |
P |
From MGI |
||
| GO:0048704 |
embryonic skeletal system morphogenesis |
MGI:MGI:76955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857496 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Izzi L et al. (2007) Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development. EMBO J 26: 3132-43 PubMed GONUTS page
- ↑ 2.0 2.1 Filosa S et al. (1997) Goosecoid and HNF-3beta genetically interact to regulate neural tube patterning during mouse embryogenesis. Development 124: 2843-54 PubMed GONUTS page
- ↑ Lee D et al. (2008) ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell 2: 497-507 PubMed GONUTS page
- ↑ 4.0 4.1 Lewis SL et al. (2007) Genetic interaction of Gsc and Dkk1 in head morphogenesis of the mouse. Mech Dev 124: 157-165 PubMed GONUTS page
- ↑ Tucker AS et al. (2004) Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution. Development 131: 1235-45 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Yamada G et al. (1995) Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death. Development 121: 2917-22 PubMed GONUTS page
- ↑ Rivera-Pérez JA et al. (1995) Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development. Development 121: 3005-12 PubMed GONUTS page
