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MGI:Grm8

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Grm8 ( synonyms: Gprc1h, mGluR8 )
Protein Name(s) glutamate receptor, metabotropic 8,
External Links
MGI MGI:1351345

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001642

group III metabotropic glutamate receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70579

F

From MGI

GO:0001642

group III metabotropic glutamate receptor activity

MGI:MGI:72270
PMID:7722646[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004871

signal transducer activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004930

G-protein coupled receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

F

From MGI

GO:0004930

G-protein coupled receptor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000337
InterPro:IPR011500
InterPro:IPR017978
InterPro:IPR017979

F

From MGI

GO:0005622

intracellular

MGI:MGI:72270
PMID:7722646[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0005887

integral to plasma membrane

MGI:MGI:3590471
PMID:16045496[2]

TAS: Traceable Author Statement

C

From MGI

GO:0005887

integral to plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70579

C

From MGI

GO:0007165

signal transduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000337
InterPro:IPR011500
InterPro:IPR017978
InterPro:IPR017979
InterPro:IPR000162
InterPro:IPR000144

P

From MGI

GO:0007196

inhibition of adenylate cyclase activity by G-protein coupled glutamate receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97555

P

From MGI

GO:0007268

synaptic transmission

MGI:MGI:3590471
PMID:16045496[2]

TAS: Traceable Author Statement

P

From MGI

GO:0007268

synaptic transmission

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70579

P

From MGI

GO:0007608

sensory perception of smell

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0552

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000337
InterPro:IPR017978
InterPro:IPR017979
InterPro:IPR000162
InterPro:IPR000144

C

From MGI

GO:0030818

negative regulation of cAMP biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00222

P

From MGI

GO:0035249

synaptic transmission, glutamatergic

MGI:MGI:3590471
PMID:16045496[2]

TAS: Traceable Author Statement

P

From MGI

GO:0035249

synaptic transmission, glutamatergic

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70579

P

From MGI

GO:0042734

presynaptic membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70579

C

From MGI

GO:0043005

neuron projection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70579

C

From MGI

GO:0043025

neuronal cell body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70579

C

From MGI

GO:0046928

regulation of neurotransmitter secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70579

P

From MGI

GO:0050896

response to stimulus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0716

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Duvoisin RM et al. (1995) A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb. J Neurosci 15: 3075-83 PubMed GONUTS page
  2. 2.0 2.1 2.2 Duvoisin RM et al. (2005) Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8. Eur J Neurosci 22: 425-36 PubMed GONUTS page
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