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MGI:Grlf1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Grlf1 ( synonyms: P190 RhoGAP, p190RhoGAP )
Protein Name(s) glucocorticoid receptor DNA binding factor 1,
External Links
MGI MGI:1929494

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001843

neural tube closure

MGI:MGI:1926242
PMID:11044403[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2448591

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005096

GTPase activator activity

MGI:MGI:1926242
PMID:11044403[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005525

GTP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001806

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008936
InterPro:IPR000198

C

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1926242
PMID:11044403[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0007165

signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008936
InterPro:IPR000198

P

From MGI

GO:0007229

integrin-mediated signaling pathway

MGI:MGI:1926242
PMID:11044403[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007264

small GTPase mediated signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001806

P

From MGI

GO:0008360

regulation of cell shape

MGI:MGI:1926242
PMID:11044403[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0015629

actin cytoskeleton

MGI:MGI:1926242
PMID:11044403[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030900

forebrain development

MGI:MGI:1926242
PMID:11044403[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2448591

P

From MGI

GO:0043010

camera-type eye development

MGI:MGI:1926242
PMID:11044403[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2448591

P

From MGI

GO:0043116

negative regulation of vascular permeability

MGI:MGI:3722538
PMID:17562701[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043547

positive regulation of GTPase activity

MGI:MGI:1926242
PMID:11044403[1]

TAS: Traceable Author Statement

P

From MGI

GO:0045892

negative regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NRY4

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Brouns MR et al. (2000) The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development 127: 4891-903 PubMed GONUTS page
  2. Mammoto T et al. (2007) Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. J Biol Chem 282: 23910-8 PubMed GONUTS page
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