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MGI:Grlf1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Grlf1 ( synonyms: P190 RhoGAP, p190RhoGAP ) | |
| Protein Name(s) | glucocorticoid receptor DNA binding factor 1, | |
| External Links | ||
| MGI | MGI:1929494 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001843 |
neural tube closure |
MGI:MGI:1926242 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2448591 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005096 |
GTPase activator activity |
MGI:MGI:1926242 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005525 |
GTP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:1926242 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007229 |
integrin-mediated signaling pathway |
MGI:MGI:1926242 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007264 |
small GTPase mediated signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008360 |
regulation of cell shape |
MGI:MGI:1926242 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0015629 |
actin cytoskeleton |
MGI:MGI:1926242 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030900 |
forebrain development |
MGI:MGI:1926242 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2448591 |
P |
From MGI |
||
| GO:0043010 |
camera-type eye development |
MGI:MGI:1926242 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2448591 |
P |
From MGI |
||
| GO:0043116 |
negative regulation of vascular permeability |
MGI:MGI:3722538 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043547 |
positive regulation of GTPase activity |
MGI:MGI:1926242 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Brouns MR et al. (2000) The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development 127: 4891-903 PubMed GONUTS page
- ↑ Mammoto T et al. (2007) Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. J Biol Chem 282: 23910-8 PubMed GONUTS page