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MGI:Grin1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Grin1 ( synonyms: GluRzeta1, M100174, Nmdar, NMDAR1, NR1, Rgsc174 ) | |
| Protein Name(s) | glutamate receptor, ionotropic, NMDA1 (zeta 1), | |
| External Links | ||
| MGI | MGI:95819 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001661 |
conditioned taste aversion |
MGI:MGI:3589959 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0001964 |
startle response |
MGI:MGI:1858680 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928283 |
P |
From MGI |
||
| GO:0001967 |
suckling behavior |
MGI:MGI:2137201 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0001967 |
suckling behavior |
MGI:MGI:65431 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0001967 |
suckling behavior |
MGI:MGI:85962 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001975 |
response to amphetamine |
MGI:MGI:3629445 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928280 |
P |
From MGI |
||
| GO:0001975 |
response to amphetamine |
MGI:MGI:3784348 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928280 |
P |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004970 |
ionotropic glutamate receptor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:1888650 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:1928326 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928327 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:2182479 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:2667460 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:3579211 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:3703316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611337 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:49860 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:49860 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95820 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:49860 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95821 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:49860 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95822 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:50809 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:51718 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:65431 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:65947 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:65947 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95820 |
F |
From MGI |
||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:68623 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004972 |
N-methyl-D-aspartate selective glutamate receptor activity |
MGI:MGI:69304 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95821 |
F |
From MGI |
||
| GO:0005102 |
receptor binding |
MGI:MGI:2155580 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005215 |
transporter activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005216 |
ion channel activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0407 |
F |
From MGI |
||
| GO:0005216 |
ion channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005234 |
extracellular-glutamate-gated ion channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005261 |
cation channel activity |
MGI:MGI:69304 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95821 |
F |
From MGI |
||
| GO:0005262 |
calcium channel activity |
MGI:MGI:50809 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005262 |
calcium channel activity |
MGI:MGI:65947 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005262 |
calcium channel activity |
MGI:MGI:65947 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95820 |
F |
From MGI |
||
| GO:0005509 |
calcium ion binding |
MGI:MGI:3526504 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1195436 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1860431 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2155580 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2682163 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3526504 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3619820 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3692803 |
IPI: Inferred from Physical Interaction |
MGI:MGI:104684 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3694290 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3835254 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4359331 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5315347 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:80545 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:85255 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005516 |
calmodulin binding |
MGI:MGI:3526504 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:1859430 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:3690398 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:81821 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:85255 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2445233 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0005887 |
integral to plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006811 |
ion transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0406 |
P |
From MGI |
||
| GO:0006811 |
ion transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006812 |
cation transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006812 |
cation transport |
MGI:MGI:69304 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95821 |
P |
From MGI |
||
| GO:0006816 |
calcium ion transport |
MGI:MGI:3622400 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178083 |
P |
From MGI |
||
| GO:0006816 |
calcium ion transport |
MGI:MGI:50809 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006874 |
cellular calcium ion homeostasis |
MGI:MGI:1928326 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928327 |
P |
From MGI |
||
| GO:0007268 |
synaptic transmission |
MGI:MGI:1859430 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007585 |
respiratory gaseous exchange |
MGI:MGI:65431 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0007585 |
respiratory gaseous exchange |
MGI:MGI:85962 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007611 |
learning or memory |
MGI:MGI:3664028 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0007612 |
learning |
MGI:MGI:3691363 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3692441 |
P |
From MGI |
||
| GO:0007613 |
memory |
MGI:MGI:1353841 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0007613 |
memory |
MGI:MGI:1353881 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0007613 |
memory |
MGI:MGI:3715411 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0007616 |
long-term memory |
MGI:MGI:3036924 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0008021 |
synaptic vesicle |
MGI:MGI:1859430 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0008306 |
associative learning |
MGI:MGI:2182479 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0008306 |
associative learning |
MGI:MGI:3621679 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0008344 |
adult locomotory behavior |
MGI:MGI:1343743 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928280 |
P |
From MGI |
||
| GO:0008344 |
adult locomotory behavior |
MGI:MGI:1858680 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928283 |
P |
From MGI |
||
| GO:0008355 |
olfactory learning |
MGI:MGI:1353841 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0008355 |
olfactory learning |
MGI:MGI:1931991 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:1858680 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928283 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:3623866 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:3703316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611337 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:84850 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:86085 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97306 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:893741 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0009986 |
cell surface |
MGI:MGI:3765383 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0010646 |
regulation of cell communication |
MGI:MGI:3610881 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0010942 |
positive regulation of cell death |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0014069 |
postsynaptic density |
MGI:MGI:3054180 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0014069 |
postsynaptic density |
MGI:MGI:3531593 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0014069 |
postsynaptic density |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:50809 |
IC: Inferred by Curator |
GO:0004972 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016594 |
glycine binding |
MGI:MGI:3687923 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0016594 |
glycine binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016594 |
glycine binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016595 |
glutamate binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016595 |
glutamate binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0017146 |
N-methyl-D-aspartate selective glutamate receptor complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0017146 |
N-methyl-D-aspartate selective glutamate receptor complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0017146 |
N-methyl-D-aspartate selective glutamate receptor complex |
MGI:MGI:85255 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0019233 |
sensory perception of pain |
MGI:MGI:2667460 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0019717 |
synaptosome |
MGI:MGI:2682163 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0021586 |
pons maturation |
MGI:MGI:65431 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0021987 |
cerebral cortex development |
MGI:MGI:1888650 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0021987 |
cerebral cortex development |
MGI:MGI:2654367 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655237 |
P |
From MGI |
||
| GO:0022843 |
voltage-gated cation channel activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030288 |
outer membrane-bounded periplasmic space |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0030425 |
dendrite |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030426 |
growth cone |
MGI:MGI:1344968 |
NAS: Non-traceable Author Statement |
C |
From MGI |
|||
| GO:0032590 |
dendrite membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0407 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:1888650 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:1928326 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928327 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:2182479 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:2667460 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:3579211 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:3703316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611337 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:65431 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0034765 |
regulation of ion transmembrane transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035176 |
social behavior |
MGI:MGI:1343743 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928280 |
P |
From MGI |
||
| GO:0035235 |
ionotropic glutamate receptor signaling pathway |
MGI:MGI:3604036 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035235 |
ionotropic glutamate receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035249 |
synaptic transmission, glutamatergic |
MGI:MGI:1888650 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0035249 |
synaptic transmission, glutamatergic |
MGI:MGI:65431 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0035254 |
glutamate receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042165 |
neurotransmitter binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:1928326 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928327 |
P |
From MGI |
||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:2182479 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:2654367 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655237 |
P |
From MGI |
||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:2667460 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:3622400 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178083 |
P |
From MGI |
||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:3703316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611337 |
P |
From MGI |
||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:50809 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3757796 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95820 |
P |
From MGI |
||
| GO:0043083 |
synaptic cleft |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043195 |
terminal button |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043197 |
dendritic spine |
MGI:MGI:3526504 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043197 |
dendritic spine |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043278 |
response to morphine |
MGI:MGI:3797147 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0043523 |
regulation of neuron apoptotic process |
MGI:MGI:1344923 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95815 |
P |
From MGI |
||
| GO:0043523 |
regulation of neuron apoptotic process |
MGI:MGI:3655891 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0043524 |
negative regulation of neuron apoptotic process |
MGI:MGI:3695621 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:99702 |
P |
From MGI |
||
| GO:0043524 |
negative regulation of neuron apoptotic process |
MGI:MGI:3695621 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0043576 |
regulation of respiratory gaseous exchange |
MGI:MGI:2137201 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045202 |
synapse |
MGI:MGI:3530687 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045202 |
synapse |
MGI:MGI:3604036 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045202 |
synapse |
MGI:MGI:3701026 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:2155573 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:2669049 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:3054180 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045471 |
response to ethanol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:65181 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048167 |
regulation of synaptic plasticity |
MGI:MGI:3036924 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0048167 |
regulation of synaptic plasticity |
MGI:MGI:84849 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0048167 |
regulation of synaptic plasticity |
MGI:MGI:84850 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0048167 |
regulation of synaptic plasticity |
MGI:MGI:893741 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0048168 |
regulation of neuronal synaptic plasticity |
MGI:MGI:3622400 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178083 |
P |
From MGI |
||
| GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
MGI:MGI:1858680 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928283 |
P |
From MGI |
||
| GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
MGI:MGI:3691363 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3692441 |
P |
From MGI |
||
| GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
MGI:MGI:3703316 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3611337 |
P |
From MGI |
||
| GO:0048511 |
rhythmic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048814 |
regulation of dendrite morphogenesis |
MGI:MGI:3579211 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0050770 |
regulation of axonogenesis |
MGI:MGI:3579211 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0050905 |
neuromuscular process |
MGI:MGI:65431 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928270 |
P |
From MGI |
||
| GO:0051963 |
regulation of synapse assembly |
MGI:MGI:2654367 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2655237 |
P |
From MGI |
||
| GO:0055074 |
calcium ion homeostasis |
MGI:MGI:65181 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0060076 |
excitatory synapse |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0060079 |
regulation of excitatory postsynaptic membrane potential |
MGI:MGI:2682163 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95821 |
P |
From MGI |
||
| GO:0060079 |
regulation of excitatory postsynaptic membrane potential |
MGI:MGI:3036924 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928279 |
P |
From MGI |
||
| GO:0060134 |
prepulse inhibition |
MGI:MGI:3051067 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928280 |
P |
From MGI |
||
| GO:0060179 |
male mating behavior |
MGI:MGI:1343743 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1928280 |
P |
From MGI |
||
| GO:0070588 |
calcium ion transmembrane transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2000463 |
positive regulation of excitatory postsynaptic membrane potential |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cui Z et al. (2005) Requirement of NMDA receptor reactivation for consolidation and storage of nondeclarative taste memory revealed by inducible NR1 knockout. Eur J Neurosci 22: 755-63 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Kew JN et al. (2000) Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site. J Neurosci 20: 4037-49 PubMed GONUTS page
- ↑ 3.0 3.1 Poon CS et al. (2000) NMDA receptor activity in utero averts respiratory depression and anomalous long-term depression in newborn mice. J Neurosci 20: RC73 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Li Y et al. (1994) Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell 76: 427-37 PubMed GONUTS page
- ↑ 5.0 5.1 Tokita Y et al. (1996) Characterization of excitatory amino acid neurotoxicity in N-methyl-D-aspartate receptor-deficient mouse cortical neuronal cells. Eur J Neurosci 8: 69-78 PubMed GONUTS page
- ↑ Moy SS et al. (2006) Amphetamine-induced disruption of prepulse inhibition in mice with reduced NMDA receptor function. Brain Res 1089: 186-94 PubMed GONUTS page
- ↑ Miyamoto S et al. (2004) Amphetamine-induced Fos is reduced in limbic cortical regions but not in the caudate or accumbens in a genetic model of NMDA receptor hypofunction. Neuropsychopharmacology 29: 2180-8 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Iwasato T et al. (2000) Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex. Nature 406: 726-31 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Forrest D et al. (1994) Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron 13: 325-38 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 Nakazawa K et al. (2002) Requirement for hippocampal CA3 NMDA receptors in associative memory recall. Science 297: 211-8 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 11.3 South SM et al. (2003) A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain. J Neurosci 23: 5031-40 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 12.3 Lee LJ et al. (2005) NMDA receptor-dependent regulation of axonal and dendritic branching. J Neurosci 25: 2304-11 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 13.3 13.4 Niewoehner B et al. (2007) Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus. Eur J Neurosci 25: 837-46 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 14.3 Kutsuwada T et al. (1992) Molecular diversity of the NMDA receptor channel. Nature 358: 36-41 PubMed GONUTS page
- ↑ 15.0 15.1 15.2 15.3 15.4 Yamazaki M et al. (1992) Cloning, expression and modulation of a mouse NMDA receptor subunit. FEBS Lett 300: 39-45 PubMed GONUTS page
- ↑ Ikeda K et al. (1992) Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel. FEBS Lett 313: 34-8 PubMed GONUTS page
- ↑ 17.0 17.1 17.2 17.3 Meguro H et al. (1992) Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Nature 357: 70-4 PubMed GONUTS page
- ↑ Chazot PL et al. (1994) Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule. J Biol Chem 269: 24403-9 PubMed GONUTS page
- ↑ 19.0 19.1 19.2 Tsuzuki K et al. (1994) Ion permeation properties of the cloned mouse epsilon 2/zeta 1 NMDA receptor channel. Brain Res Mol Brain Res 26: 37-46 PubMed GONUTS page
- ↑ 20.0 20.1 Grunwald IC et al. (2001) Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity. Neuron 32: 1027-40 PubMed GONUTS page
- ↑ 21.0 21.1 21.2 21.3 Amparan D et al. (2005) Direct interaction of myosin regulatory light chain with the NMDA receptor. J Neurochem 92: 349-61 PubMed GONUTS page
- ↑ Sprengel R et al. (1998) Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell 92: 279-89 PubMed GONUTS page
- ↑ Husi H et al. (2000) Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nat Neurosci 3: 661-9 PubMed GONUTS page
- ↑ 24.0 24.1 24.2 Köhr G et al. (2003) Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction. J Neurosci 23: 10791-9 PubMed GONUTS page
- ↑ Son GH et al. (2006) Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity. J Neurosci 26: 3309-18 PubMed GONUTS page
- ↑ Offenhäuser N et al. (2006) Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell 127: 213-26 PubMed GONUTS page
- ↑ Hoe HS et al. (2006) Apolipoprotein E receptor 2 interactions with the N-methyl-D-aspartate receptor. J Biol Chem 281: 3425-31 PubMed GONUTS page
- ↑ Bajaj G et al. (2009) N-methyl-D-aspartate receptor subunits are non-myosin targets of myosin regulatory light chain. J Biol Chem 284: 1252-66 PubMed GONUTS page
- ↑ Fernández E et al. (2009) Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Mol Syst Biol 5: 269 PubMed GONUTS page
- ↑ Collins MO et al. (2006) Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome. J Neurochem 97 Suppl 1: 16-23 PubMed GONUTS page
- ↑ Didier M et al. (1995) Differential expression and co-assembly of NMDA zeta 1 and epsilon subunits in the mouse cerebellum during postnatal development. Neuroreport 6: 2255-9 PubMed GONUTS page
- ↑ 32.0 32.1 32.2 Chazot PL & Stephenson FA (1997) Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor. J Neurochem 68: 507-16 PubMed GONUTS page
- ↑ 33.0 33.1 33.2 Setou M et al. (2000) Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science 288: 1796-802 PubMed GONUTS page
- ↑ Lai C et al. (2006) Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. J Neurosci 26: 11798-806 PubMed GONUTS page
- ↑ Snell LD et al. (1996) Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion. Brain Res Mol Brain Res 40: 71-8 PubMed GONUTS page
- ↑ Puyal J et al. (2002) Distribution of alpha-amino-3-hydroxy-5-methyl-4 isoazolepropionic acid and N-methyl-D-aspartate receptor subunits in the vestibular and spiral ganglia of the mouse during early development. Brain Res Dev Brain Res 139: 51-7 PubMed GONUTS page
- ↑ 37.0 37.1 37.2 Pawlak V et al. (2005) Impaired synaptic scaling in mouse hippocampal neurones expressing NMDA receptors with reduced calcium permeability. J Physiol 562: 771-83 PubMed GONUTS page
- ↑ Cravens CJ et al. (2006) CA3 NMDA receptors are crucial for rapid and automatic representation of context memory. Eur J Neurosci 24: 1771-80 PubMed GONUTS page
- ↑ 39.0 39.1 Dang MT et al. (2006) Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum. Proc Natl Acad Sci U S A 103: 15254-9 PubMed GONUTS page
- ↑ 40.0 40.1 Rampon C et al. (2000) Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice. Nat Neurosci 3: 238-44 PubMed GONUTS page
- ↑ Huerta PT et al. (2000) Formation of temporal memory requires NMDA receptors within CA1 pyramidal neurons. Neuron 25: 473-80 PubMed GONUTS page
- ↑ McHugh TJ et al. (2007) Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network. Science 317: 94-9 PubMed GONUTS page
- ↑ 43.0 43.1 43.2 Cui Z et al. (2004) Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain. Neuron 41: 781-93 PubMed GONUTS page
- ↑ Nakazawa K et al. (2003) Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience. Neuron 38: 305-15 PubMed GONUTS page
- ↑ 45.0 45.1 45.2 Mohn AR et al. (1999) Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98: 427-36 PubMed GONUTS page
- ↑ Rondi-Reig L et al. (2001) CA1-specific N-methyl-D-aspartate receptor knockout mice are deficient in solving a nonspatial transverse patterning task. Proc Natl Acad Sci U S A 98: 3543-8 PubMed GONUTS page
- ↑ Rondi-Reig L et al. (2006) Impaired sequential egocentric and allocentric memories in forebrain-specific-NMDA receptor knock-out mice during a new task dissociating strategies of navigation. J Neurosci 26: 4071-81 PubMed GONUTS page
- ↑ 48.0 48.1 Tsien JZ et al. (1996) The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87: 1327-38 PubMed GONUTS page
- ↑ Silva AJ et al. (1997) A mouse model for the learning and memory deficits associated with neurofibromatosis type I. Nat Genet 15: 281-4 PubMed GONUTS page
- ↑ 50.0 50.1 Tonegawa S et al. (1996) Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning. Cold Spring Harb Symp Quant Biol 61: 225-38 PubMed GONUTS page
- ↑ Qiu S & Weeber EJ (2007) Reelin signaling facilitates maturation of CA1 glutamatergic synapses. J Neurophysiol 97: 2312-21 PubMed GONUTS page
- ↑ Arumugam H et al. (2005) NMDA receptors regulate developmental gap junction uncoupling via CREB signaling. Nat Neurosci 8: 1720-6 PubMed GONUTS page
- ↑ 53.0 53.1 Abe M et al. (2004) NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit. J Neurosci 24: 7292-304 PubMed GONUTS page
- ↑ Trinidad JC et al. (2005) Phosphorylation state of postsynaptic density proteins. J Neurochem 92: 1306-16 PubMed GONUTS page
- ↑ Kiefer F et al. (2003) Involvement of NMDA receptors in alcohol-mediated behavior: mice with reduced affinity of the NMDA R1 glycine binding site display an attenuated sensitivity to ethanol. Biol Psychiatry 53: 345-51 PubMed GONUTS page
- ↑ 56.0 56.1 56.2 Rudhard Y et al. (2003) Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling. J Neurosci 23: 2323-32 PubMed GONUTS page
- ↑ Chen LT et al. (1999) A candidate target for G protein action in brain. J Biol Chem 274: 26931-8 PubMed GONUTS page
- ↑ 58.0 58.1 Snyder EM et al. (2005) Regulation of NMDA receptor trafficking by amyloid-beta. Nat Neurosci 8: 1051-8 PubMed GONUTS page
- ↑ Taniura H et al. (2007) Tex261 modulates the excitotoxic cell death induced by N-methyl-D-aspartate (NMDA) receptor activation. Biochem Biophys Res Commun 362: 1096-100 PubMed GONUTS page
- ↑ Quintero GC et al. (2008) Evaluation of morphine analgesia and motor coordination in mice following cortex-specific knockout of the N-methyl-D-aspartate NR1-subunit. Neurosci Lett 437: 55-8 PubMed GONUTS page
- ↑ Jensen P et al. (1999) Rescue of cerebellar granule cells from death in weaver NR1 double mutants. J Neurosci 19: 7991-8 PubMed GONUTS page
- ↑ Tashiro A et al. (2006) NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus. Nature 442: 929-33 PubMed GONUTS page
- ↑ 63.0 63.1 de Rivero Vaccari JC et al. (2006) NMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell death. Proc Natl Acad Sci U S A 103: 16971-6 PubMed GONUTS page
- ↑ Chih B et al. (2005) Control of excitatory and inhibitory synapse formation by neuroligins. Science 307: 1324-8 PubMed GONUTS page
- ↑ Nakazawa T et al. (2006) NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. EMBO J 25: 2867-77 PubMed GONUTS page
- ↑ Henderson JT et al. (2001) The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function. Neuron 32: 1041-56 PubMed GONUTS page
- ↑ Tao YX et al. (2003) Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein. J Neurosci 23: 6703-12 PubMed GONUTS page
- ↑ 68.0 68.1 Bulleit RF et al. (1994) NMDA receptor activation in differentiating cerebellar cell cultures regulates the expression of a new POU gene, Cns-1. J Neurosci 14: 1584-95 PubMed GONUTS page
- ↑ McHugh TJ et al. (1996) Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice. Cell 87: 1339-49 PubMed GONUTS page
- ↑ Duncan GE et al. (2004) Deficits in sensorimotor gating and tests of social behavior in a genetic model of reduced NMDA receptor function. Behav Brain Res 153: 507-19 PubMed GONUTS page
