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MGI:Grid2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Grid2 ( synonyms: GluRdelta2, tpr ) | |
| Protein Name(s) | glutamate receptor, ionotropic, delta 2, | |
| External Links | ||
| MGI | MGI:95813 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004970 |
ionotropic glutamate receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005215 |
transporter activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005216 |
ion channel activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0407 |
F |
From MGI |
||
| GO:0005216 |
ion channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005234 |
extracellular-glutamate-gated ion channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2158592 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2385984 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3603702 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3851319 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3852309 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4839424 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:3603702 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3852309 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006811 |
ion transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0406 |
P |
From MGI |
||
| GO:0006811 |
ion transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008328 |
ionotropic glutamate receptor complex |
MGI:MGI:3852309 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0014069 |
postsynaptic density |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0019717 |
synaptosome |
MGI:MGI:2385984 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030165 |
PDZ domain binding |
MGI:MGI:3852309 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0030165 |
PDZ domain binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030288 |
outer membrane-bounded periplasmic space |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0407 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0034613 |
cellular protein localization |
MGI:MGI:3852309 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035249 |
synaptic transmission, glutamatergic |
MGI:MGI:72217 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178052 |
P |
From MGI |
||
| GO:0043197 |
dendritic spine |
MGI:MGI:3852309 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043523 |
regulation of neuron apoptotic process |
MGI:MGI:1861056 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:99702 |
P |
From MGI |
||
| GO:0043523 |
regulation of neuron apoptotic process |
MGI:MGI:1861056 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857337 |
P |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:3796257 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:3852309 |
IC: Inferred by Curator |
GO:0019717 |
C |
From MGI |
||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0060079 |
regulation of excitatory postsynaptic membrane potential |
MGI:MGI:72217 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178052 |
P |
From MGI |
||
| GO:0060134 |
prepulse inhibition |
MGI:MGI:3040117 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2178052 |
P |
From MGI |
||
| GO:0097110 |
scaffold protein binding |
MGI:MGI:3852309 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Miyagi Y et al. (2002) Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit. J Neurosci 22: 803-14 PubMed GONUTS page
- ↑ 2.0 2.1 Yue Z et al. (2002) A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron 35: 921-33 PubMed GONUTS page
- ↑ 3.0 3.1 Nakamura M et al. (2004) Signaling complex formation of phospholipase Cbeta4 with metabotropic glutamate receptor type 1alpha and 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain. Eur J Neurosci 20: 2929-44 PubMed GONUTS page
- ↑ Yamashita T et al. (2005) Identification and characterization of a novel Delphilin variant with an alternative N-terminus. Brain Res Mol Brain Res 141: 83-94 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 Uemura T et al. (2004) Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells. Mol Cell Neurosci 26: 330-41 PubMed GONUTS page
- ↑ Uemura T et al. (2010) Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum. Cell 141: 1068-79 PubMed GONUTS page
- ↑ 7.0 7.1 Hirano T et al. (1995) Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit. Neuroreport 6: 524-6 PubMed GONUTS page
- ↑ 8.0 8.1 Selimi F et al. (2000) Bax inactivation in lurcher mutants rescues cerebellar granule cells but not purkinje cells or inferior olivary neurons. J Neurosci 20: 5339-45 PubMed GONUTS page
- ↑ Takeuchi T et al. (2008) Enhancement of both long-term depression induction and optokinetic response adaptation in mice lacking delphilin. PLoS One 3: e2297 PubMed GONUTS page
- ↑ Takeuchi T et al. (2001) Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex. Eur J Neurosci 14: 153-60 PubMed GONUTS page
