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MGI:Gpihbp1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Gpihbp1 ( synonyms: GPI-HBP1 ) | |
| Protein Name(s) | GPI-anchored HDL-binding protein 1, | |
| External Links | ||
| MGI | MGI:1915703 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005622 |
intracellular |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006869 |
lipid transport |
MGI:MGI:2451215 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006886 |
intracellular protein transport |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008035 |
high-density lipoprotein particle binding |
MGI:MGI:2451215 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008289 |
lipid binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0446 |
F |
From MGI |
||
| GO:0008320 |
protein transmembrane transporter activity |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:3770110 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:2451215 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016323 |
basolateral plasma membrane |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0017038 |
protein import |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0031362 |
anchored to external side of plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0034185 |
apolipoprotein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0034364 |
high-density lipoprotein particle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0345 |
C |
From MGI |
||
| GO:0034394 |
protein localization at cell surface |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035473 |
lipase binding |
MGI:MGI:3770110 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0035473 |
lipase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035478 |
chylomicron binding |
MGI:MGI:3770110 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0035478 |
chylomicron binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042632 |
cholesterol homeostasis |
MGI:MGI:3770110 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045056 |
transcytosis |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046658 |
anchored to plasma membrane |
MGI:MGI:2451215 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0050821 |
protein stabilization |
MGI:MGI:4412214 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051006 |
positive regulation of lipoprotein lipase activity |
MGI:MGI:3770110 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051006 |
positive regulation of lipoprotein lipase activity |
MGI:MGI:4412214 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051006 |
positive regulation of lipoprotein lipase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0055085 |
transmembrane transport |
MGI:MGI:4820887 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070328 |
triglyceride homeostasis |
MGI:MGI:3770110 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070328 |
triglyceride homeostasis |
MGI:MGI:4412214 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0070328 |
triglyceride homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071503 |
response to heparin |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071813 |
lipoprotein particle binding |
MGI:MGI:3770110 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0071813 |
lipoprotein particle binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0090319 |
positive regulation of chylomicron remodeling |
MGI:MGI:3770110 |
IC: Inferred by Curator |
GO:0051006 |
P |
From MGI |
||
| GO:0090321 |
positive regulation of chylomicron remnant clearance |
MGI:MGI:3770110 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
|
NOT |
GO:0030301 |
cholesterol transport |
MGI:MGI:2451215 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Davies BS et al. (2010) GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries. Cell Metab 12: 42-52 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Ioka RX et al. (2003) Expression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1. J Biol Chem 278: 7344-9 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 Beigneux AP et al. (2007) Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab 5: 279-91 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Sonnenburg WK et al. (2009) GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4. J Lipid Res 50: 2421-9 PubMed GONUTS page
