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MGI:Got1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Got1 ( synonyms: cAspAT, cytosolic aspartate aminotransferase, Got-1 )
Protein Name(s) glutamate oxaloacetate transaminase 1, soluble,
External Links
MGI MGI:95791

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004838
InterPro:IPR015421

F

From MGI

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

MGI:MGI:3722000
PMID:17545671[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13221

F

From MGI

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P17174

F

From MGI

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

MGI:MGI:48978
PMID:1914521[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

MGI:MGI:52934

IDA: Inferred from Direct Assay

F

From MGI

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

MGI:MGI:54917
PMID:7444718[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004609

phosphatidylserine decarboxylase activity

MGI:MGI:58172
PMID:3242498[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005625

soluble fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13221

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13221

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P17174

C

From MGI

GO:0005764

lysosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13221

C

From MGI

GO:0005829

cytosol

MGI:MGI:52934

IDA: Inferred from Direct Assay

C

From MGI

GO:0005829

cytosol

MGI:MGI:53641
PMID:4193185[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006107

oxaloacetate metabolic process

MGI:MGI:53641
PMID:4193185[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006114

glycerol biosynthetic process

MGI:MGI:3722000
PMID:17545671[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006520

cellular amino acid metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000796

P

From MGI

GO:0006531

aspartate metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13221

P

From MGI

GO:0006532

aspartate biosynthetic process

MGI:MGI:53641
PMID:4193185[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006533

aspartate catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P17174

P

From MGI

GO:0008483

transaminase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0032

F

From MGI

GO:0008483

transaminase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000796

F

From MGI

GO:0009058

biosynthetic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004839
InterPro:IPR004838

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016740

transferase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004839

F

From MGI

GO:0019550

glutamate catabolic process to aspartate

MGI:MGI:53641
PMID:4193185[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0019551

glutamate catabolic process to 2-oxoglutarate

MGI:MGI:53641
PMID:4193185[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030170

pyridoxal phosphate binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004839
InterPro:IPR004838
InterPro:IPR015421

F

From MGI

GO:0031406

carboxylic acid binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13221

F

From MGI

GO:0043648

dicarboxylic acid metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13221

P

From MGI

GO:0043679

axon terminus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13221

C

From MGI

GO:0055089

fatty acid homeostasis

MGI:MGI:3722000
PMID:17545671[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0080130

L-phenylalanine:2-oxoglutarate aminotransferase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.6.1.1

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Tordjman J et al. (2007) Cytosolic aspartate aminotransferase, a new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedione. J Biol Chem 282: 23591-602 PubMed GONUTS page
  2. Yasue M et al. (1991) Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids. Cytogenet Cell Genet 57: 142-8 PubMed GONUTS page
  3. Schäfer R et al. (1980) Assignment of the gene for cytoplasmic glutamate-oxaloacetate transaminase to mouse chromosome 19 using chinese hamster x mouse somatic cell hybrids. Somatic Cell Genet 6: 709-17 PubMed GONUTS page
  4. von Deimling OH et al. (1988) Esterase-18 (ES-18) of the house mouse (Mus musculus): biochemical characterization and genetics of an allozyme system linked to chromosome 19. Biochem Genet 26: 617-29 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 DeLorenzo RJ & Ruddle FH (1970) Glutamate oxalate transaminase (GOT) genetics in Mus musculus: linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci. Biochem Genet 4: 259-73 PubMed GONUTS page
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