Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Gnb2l1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Gnb2l1 ( synonyms: GB-like, Gnb2-rs1, p205, Rack1 )
Protein Name(s) guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1,
External Links
MGI MGI:101849

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001891

phagocytic cup

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

C

From MGI

GO:0001934

positive regulation of protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0004872

receptor activity

MGI:MGI:1927965
PMID:11099474[1]

ISA: Inferred from Sequence Alignment

EMBL:AJ132860

F

From MGI

GO:0005080

protein kinase C binding

MGI:MGI:1927965
PMID:11099474[1]

ISA: Inferred from Sequence Alignment

EMBL:AJ132860

F

From MGI

GO:0005080

protein kinase C binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63245

F

From MGI

GO:0005080

protein kinase C binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

F

From MGI

GO:0005515

protein binding

MGI:MGI:3688344
PMID:15102471[2]

IPI: Inferred from Physical Interaction

UniProtKB:O88351

F

From MGI

GO:0005515

protein binding

MGI:MGI:3793387
PMID:18258429[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q9BX84

F

From MGI

GO:0005515

protein binding

MGI:MGI:4939857
PMID:21262816[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q91ZD4

F

From MGI

GO:0005622

intracellular

MGI:MGI:1927965
PMID:11099474[1]

ISA: Inferred from Sequence Alignment

EMBL:AJ132860

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2675925
PMID:12826667[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006417

regulation of translation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0810

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0053

P

From MGI

GO:0007049

cell cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007369

gastrulation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0306

P

From MGI

GO:0008104

protein localization

MGI:MGI:1927965
PMID:11099474[1]

ISA: Inferred from Sequence Alignment

EMBL:AJ132860

P

From MGI

GO:0008200

ion channel inhibitor activity

MGI:MGI:3793387
PMID:18258429[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0015935

small ribosomal subunit

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63245

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0017148

negative regulation of translation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63245

P

From MGI

GO:0019903

protein phosphatase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

F

From MGI

GO:0030292

protein tyrosine kinase inhibitor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

F

From MGI

GO:0030308

negative regulation of cell growth

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0030335

positive regulation of cell migration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0030425

dendrite

MGI:MGI:3616942
PMID:16414032[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030496

midbody

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

C

From MGI

GO:0030971

receptor tyrosine kinase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

F

From MGI

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0032464

positive regulation of protein homooligomerization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0035556

intracellular signal transduction

MGI:MGI:1927965
PMID:11099474[1]

ISA: Inferred from Sequence Alignment

EMBL:AJ132860

P

From MGI

GO:0040008

regulation of growth

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0341

P

From MGI

GO:0042169

SH2 domain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

F

From MGI

GO:0042326

negative regulation of phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0043025

neuronal cell body

MGI:MGI:3616942
PMID:16414032[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043065

positive regulation of apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0043547

positive regulation of GTPase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

C

From MGI

GO:0048511

rhythmic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0090

P

From MGI

GO:0050765

negative regulation of phagocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0051726

regulation of cell cycle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0061099

negative regulation of protein tyrosine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI

GO:0090003

regulation of establishment of protein localization in plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63245

P

From MGI

GO:2001244

positive regulation of intrinsic apoptotic signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P63244

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Berns H et al. (2000) RACK1 is up-regulated in angiogenesis and human carcinomas. FASEB J 14: 2549-58 PubMed GONUTS page
  2. Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
  3. 3.0 3.1 Cao G et al. (2008) RACK1 inhibits TRPM6 activity via phosphorylation of the fused alpha-kinase domain. Curr Biol 18: 168-76 PubMed GONUTS page
  4. Li S et al. (2011) Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity. Proc Natl Acad Sci U S A 108: 2264-9 PubMed GONUTS page
  5. Wang WL et al. (2003) PICK1, an anchoring protein that specifically targets protein kinase Calpha to mitochondria selectively upon serum stimulation in NIH 3T3 cells. J Biol Chem 278: 37705-12 PubMed GONUTS page
  6. 6.0 6.1 Ashique AM et al. (2006) Localization of the scaffolding protein RACK1 in the developing and adult mouse brain. Brain Res 1069: 31-8 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox