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MGI:Gnat3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Gnat3 ( synonyms: alpha-gustducin, Ggust, Gtn )
Protein Name(s) guanine nucleotide binding protein, alpha transducing 3,
External Links
MGI MGI:3588268

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0001580

detection of chemical stimulus involved in sensory perception of bitter taste

MGI:MGI:4459044

PANTHER:PTHR10218

P

From MGI

GO:0001664

G-protein coupled receptor binding

MGI:MGI:4459044

PANTHER:PTHR10218

F

From MGI

GO:0001750

photoreceptor outer segment

MGI:MGI:4459044

PANTHER:PTHR10218

C

From MGI

GO:0001917

photoreceptor inner segment

MGI:MGI:4459044

PANTHER:PTHR10218

C

From MGI

GO:0003924

GTPase activity

MGI:MGI:1932393
PMID:10570481[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003924

GTPase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29348

F

From MGI

GO:0004871

signal transducer activity

MGI:MGI:4459044

PANTHER:PTHR10218

F

From MGI

GO:0005525

GTP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29348

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29348

C

From MGI

GO:0005834

heterotrimeric G-protein complex

MGI:MGI:1932393
PMID:10570481[1]

IPI: Inferred from Physical Interaction

UniProtKB:P04901
protein_id:AAK40268

C

From MGI

GO:0006184

GTP catabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29348

P

From MGI

GO:0007165

signal transduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

From MGI

GO:0007165

signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011025

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:1932393
PMID:10570481[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007188

G-protein signaling, coupled to cAMP nucleotide second messenger

MGI:MGI:4459044

PANTHER:PTHR10218

P

From MGI

GO:0009586

rhodopsin mediated phototransduction

MGI:MGI:4459044

PANTHER:PTHR10218

P

From MGI

GO:0016324

apical plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29348

C

From MGI

GO:0019001

guanyl nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001019

F

From MGI

GO:0031234

extrinsic to internal side of plasma membrane

MGI:MGI:4459044

PANTHER:PTHR10218

C

From MGI

GO:0031683

G-protein beta/gamma-subunit complex binding

MGI:MGI:4459044

PANTHER:PTHR10218

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0050909

sensory perception of taste

MGI:MGI:1932393
PMID:10570481[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050909

sensory perception of taste

MGI:MGI:84298
PMID:8657284[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2152966

P

From MGI

GO:0050913

sensory perception of bitter taste

MGI:MGI:3054152
PMID:15342734[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2152966

P

From MGI

GO:0050913

sensory perception of bitter taste

MGI:MGI:3763591
PMID:12379596[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2152966

P

From MGI

GO:0050916

sensory perception of sweet taste

MGI:MGI:3054152
PMID:15342734[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2152966

P

From MGI

GO:0050917

sensory perception of umami taste

MGI:MGI:3054152
PMID:15342734[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2152966

P

From MGI

GO:0050917

sensory perception of umami taste

MGI:MGI:3763591
PMID:12379596[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2152966

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Huang L et al. (1999) Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. Nat Neurosci 2: 1055-62 PubMed GONUTS page
  2. Wong GT et al. (1996) Transduction of bitter and sweet taste by gustducin. Nature 381: 796-800 PubMed GONUTS page
  3. 3.0 3.1 3.2 He W et al. (2004) Umami taste responses are mediated by alpha-transducin and alpha-gustducin. J Neurosci 24: 7674-80 PubMed GONUTS page
  4. 4.0 4.1 He W et al. (2002) Partial rescue of taste responses of alpha-gustducin null mice by transgenic expression of alpha-transducin. Chem Senses 27: 719-27 PubMed GONUTS page
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