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MGI:Gnao1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Gnao1 ( synonyms: alphaO, Galphao, Go alpha ) | |
| Protein Name(s) | guanine nucleotide binding protein, alpha O, | |
| External Links | ||
| MGI | MGI:95775 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0003924 |
GTPase activity |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0003924 |
GTPase activity |
MGI:MGI:5009199 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003924 |
GTPase activity |
MGI:MGI:58524 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004871 |
signal transducer activity |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0005525 |
GTP binding |
MGI:MGI:1932004 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152685 |
F |
From MGI |
||
| GO:0005525 |
GTP binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3640737 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:66779 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005834 |
heterotrimeric G-protein complex |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
C |
From MGI |
|||
| GO:0005834 |
heterotrimeric G-protein complex |
MGI:MGI:58524 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0006184 |
GTP catabolic process |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:1202208 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152685 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:58524 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007188 |
G-protein signaling, coupled to cAMP nucleotide second messenger |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
P |
From MGI |
|||
| GO:0007212 |
dopamine receptor signaling pathway |
MGI:MGI:1932004 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152685 |
P |
From MGI |
||
| GO:0007568 |
aging |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007626 |
locomotory behavior |
MGI:MGI:1202208 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152685 |
P |
From MGI |
||
| GO:0008016 |
regulation of heart contraction |
MGI:MGI:86399 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152683 |
P |
From MGI |
||
| GO:0009987 |
cellular process |
MGI:MGI:1349229 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152683 |
P |
From MGI |
||
| GO:0010243 |
response to organic nitrogen |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019001 |
guanyl nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0019717 |
synaptosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031234 |
extrinsic to internal side of plasma membrane |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
C |
From MGI |
|||
| GO:0031683 |
G-protein beta/gamma-subunit complex binding |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0031821 |
G-protein coupled serotonin receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0031821 |
G-protein coupled serotonin receptor binding |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0031852 |
mu-type opioid receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043547 |
positive regulation of GTPase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0051430 |
corticotropin-releasing hormone receptor 1 binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051926 |
negative regulation of calcium ion transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Traver S et al. (2000) RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. Biochem J 350 Pt 1: 19-29 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Strathmann M et al. (1989) Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Proc Natl Acad Sci U S A 86: 7407-9 PubMed GONUTS page
- ↑ 3.0 3.1 Jiang M et al. (2001) Most central nervous system D2 dopamine receptors are coupled to their effectors by Go. Proc Natl Acad Sci U S A 98: 3577-82 PubMed GONUTS page
- ↑ Fleischer J et al. (2006) Olfactory receptors and signalling elements in the Grueneberg ganglion. J Neurochem 98: 543-54 PubMed GONUTS page
- ↑ Schmidt CJ et al. (1994) G(O), a guanine nucleotide binding protein, is expressed during neurite extension in the embryonic mouse. J Neurosci Res 38: 182-7 PubMed GONUTS page
- ↑ 6.0 6.1 Jiang M et al. (1998) Multiple neurological abnormalities in mice deficient in the G protein Go. Proc Natl Acad Sci U S A 95: 3269-74 PubMed GONUTS page
- ↑ Valenzuela D et al. (1997) G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart. Proc Natl Acad Sci U S A 94: 1727-32 PubMed GONUTS page
- ↑ Tanaka M et al. (1999) G(o) protein-dependent survival of primary accessory olfactory neurons. Proc Natl Acad Sci U S A 96: 14106-11 PubMed GONUTS page
