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MGI:Gnal
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Gnal ( synonyms: G alpha 10, Galphaolf, Gna10, Golf ) | |
| Protein Name(s) | guanine nucleotide binding protein, alpha stimulating, olfactory type, | |
| External Links | ||
| MGI | MGI:95774 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0001664 |
G-protein coupled receptor binding |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0001975 |
response to amphetamine |
MGI:MGI:3719553 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2151207 |
P |
From MGI |
||
| GO:0003924 |
GTPase activity |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0003924 |
GTPase activity |
MGI:MGI:58524 |
ISA: Inferred from Sequence Alignment |
EMBL:U38501 |
F |
From MGI |
||
| GO:0004016 |
adenylate cyclase activity |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0004871 |
signal transducer activity |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0005525 |
GTP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0342 |
F |
From MGI |
||
| GO:0005525 |
GTP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3701153 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95777 |
C |
From MGI |
||
| GO:0005622 |
intracellular |
MGI:MGI:78329 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005834 |
heterotrimeric G-protein complex |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
C |
From MGI |
|||
| GO:0005834 |
heterotrimeric G-protein complex |
MGI:MGI:58524 |
ISA: Inferred from Sequence Alignment |
EMBL:U38501 |
C |
From MGI |
||
| GO:0006171 |
cAMP biosynthetic process |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
P |
From MGI |
|||
| GO:0006184 |
GTP catabolic process |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
P |
From MGI |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:58524 |
ISA: Inferred from Sequence Alignment |
EMBL:U38501 |
P |
From MGI |
||
| GO:0007189 |
activation of adenylate cyclase activity by G-protein signaling pathway |
MGI:MGI:78329 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007190 |
activation of adenylate cyclase activity |
MGI:MGI:2450485 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007191 |
activation of adenylate cyclase activity by dopamine receptor signaling pathway |
MGI:MGI:3701153 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95777 |
P |
From MGI |
||
| GO:0007608 |
sensory perception of smell |
MGI:MGI:1195583 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2151207 |
P |
From MGI |
||
| GO:0019001 |
guanyl nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0031000 |
response to caffeine |
MGI:MGI:3719553 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2151207 |
P |
From MGI |
||
| GO:0031234 |
extrinsic to internal side of plasma membrane |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
C |
From MGI |
|||
| GO:0031683 |
G-protein beta/gamma-subunit complex binding |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0050827 |
toxin receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hervé D et al. (2001) Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum. J Neurosci 21: 4390-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Strathmann M et al. (1989) Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Proc Natl Acad Sci U S A 86: 7407-9 PubMed GONUTS page
- ↑ 3.0 3.1 Rashid AJ et al. (2007) D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum. Proc Natl Acad Sci U S A 104: 654-9 PubMed GONUTS page
- ↑ 4.0 4.1 Jones DT & Reed RR (1989) Golf: an olfactory neuron specific-G protein involved in odorant signal transduction. Science 244: 790-5 PubMed GONUTS page
- ↑ Schwindinger WF et al. (2003) Loss of G protein gamma 7 alters behavior and reduces striatal alpha(olf) level and cAMP production. J Biol Chem 278: 6575-9 PubMed GONUTS page
- ↑ Belluscio L et al. (1998) Mice deficient in G(olf) are anosmic. Neuron 20: 69-81 PubMed GONUTS page