GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Gnai3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Gnai3 ( synonyms: Galphai3 ) | |
| Protein Name(s) | guanine nucleotide binding protein (G protein), alpha inhibiting 3, | |
| External Links | ||
| MGI | MGI:95773 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0003924 |
GTPase activity |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0003924 |
GTPase activity |
MGI:MGI:58524 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004871 |
signal transducer activity |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3688344 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005525 |
GTP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0342 |
F |
From MGI |
||
| GO:0005525 |
GTP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:65244 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:65244 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005834 |
heterotrimeric G-protein complex |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
C |
From MGI |
|||
| GO:0005834 |
heterotrimeric G-protein complex |
MGI:MGI:58524 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006184 |
GTP catabolic process |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
P |
From MGI |
|||
| GO:0006906 |
vesicle fusion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:58524 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007193 |
inhibition of adenylate cyclase activity by G-protein signaling pathway |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0019001 |
guanyl nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030496 |
midbody |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031234 |
extrinsic to internal side of plasma membrane |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
C |
From MGI |
|||
| GO:0031683 |
G-protein beta/gamma-subunit complex binding |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0031821 |
G-protein coupled serotonin receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0031821 |
G-protein coupled serotonin receptor binding |
MGI:MGI:4459044 |
PANTHER:PTHR10218 |
F |
From MGI |
|||
| GO:0042588 |
zymogen granule |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045121 |
membrane raft |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0051301 |
cell division |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
NOT |
GO:0008016 |
regulation of heart contraction |
MGI:MGI:1931975 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2152617 |
P |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Strathmann M et al. (1989) Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. Proc Natl Acad Sci U S A 86: 7407-9 PubMed GONUTS page
- ↑ Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
- ↑ 3.0 3.1 Cadrin M et al. (1993) Identification and localization of G(i) alpha 3 in the clonal adipocyte cell lines HGFu and Ob17. Biochem Cell Biol 71: 518-21 PubMed GONUTS page
- ↑ Jain M et al. (2001) Targeted inactivation of Galpha(i) does not alter cardiac function or beta-adrenergic sensitivity. Am J Physiol Heart Circ Physiol 280: H569-75 PubMed GONUTS page
