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MGI:Gmnn
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Gmnn ( synonyms: Gem ) | |
| Protein Name(s) | geminin, | |
| External Links | ||
| MGI | MGI:1927344 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:3663964 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2388867 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3038045 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3663964 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3693385 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1277797 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006461 |
protein complex assembly |
MGI:MGI:3663964 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0008156 |
negative regulation of DNA replication |
MGI:MGI:2388867 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008156 |
negative regulation of DNA replication |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009887 |
organ morphogenesis |
MGI:MGI:1277797 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042826 |
histone deacetylase binding |
MGI:MGI:3663964 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0042826 |
histone deacetylase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045786 |
negative regulation of cell cycle |
MGI:MGI:2388867 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045786 |
negative regulation of cell cycle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:3663964 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070491 |
repressing transcription factor binding |
MGI:MGI:3663964 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
|
NOT |
GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:3663964 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Kim MY et al. (2006) A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. Proc Natl Acad Sci U S A 103: 13074-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Yanagi K et al. (2002) Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity. J Biol Chem 277: 40871-80 PubMed GONUTS page
- ↑ Luo L et al. (2004) The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions. Nature 427: 749-53 PubMed GONUTS page
- ↑ Lee C et al. (2004) Structural basis for inhibition of the replication licensing factor Cdt1 by geminin. Nature 430: 913-7 PubMed GONUTS page
- ↑ 5.0 5.1 Kroll KL et al. (1998) Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation. Development 125: 3247-58 PubMed GONUTS page
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