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MGI:Glul

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Glul ( synonyms: Glns, GS )
Protein Name(s) glutamate-ammonia ligase (glutamine synthetase),
External Links
MGI MGI:95739

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000287

magnesium ion binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR014746

F

From MGI

GO:0004351

glutamate decarboxylase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:4.1.1.15

F

From MGI

GO:0004356

glutamate-ammonia ligase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

F

From MGI

GO:0005515

protein binding

MGI:MGI:5009408
PMID:16323283[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9JHU2

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

F

From MGI

GO:0005622

intracellular

MGI:MGI:1261747
PMID:9628326[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005622

intracellular

MGI:MGI:3610839
PMID:15964665[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005625

soluble fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2673754
PMID:12923239[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P15104

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005791

rough endoplasmic reticulum

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0005792

microsome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P15104

C

From MGI

GO:0006536

glutamate metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

P

From MGI

GO:0006542

glutamine biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

P

From MGI

GO:0006807

nitrogen compound metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008147
InterPro:IPR008146

P

From MGI

GO:0008283

cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P15104

P

From MGI

GO:0009749

response to glucose stimulus

MGI:MGI:3767902
PMID:17854388[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2180159

P

From MGI

GO:0016595

glutamate binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

F

From MGI

GO:0016829

lyase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0456

F

From MGI

GO:0016874

ligase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0436

F

From MGI

GO:0019676

ammonia assimilation cycle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

P

From MGI

GO:0019717

synaptosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0030145

manganese ion binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

F

From MGI

GO:0032024

positive regulation of insulin secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

P

From MGI

GO:0042802

identical protein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P15104

F

From MGI

GO:0042995

cell projection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0043204

perikaryon

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0043234

protein complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0043679

axon terminus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

GO:0045503

dynein light chain binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

F

From MGI

GO:0050679

positive regulation of epithelial cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

P

From MGI

GO:0051260

protein homooligomerization

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

P

From MGI

GO:0051968

positive regulation of synaptic transmission, glutamatergic

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

P

From MGI

NOT

GO:0019717

synaptosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI

NOT

GO:0043679

axon terminus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09606

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Hu B et al. (2005) Molecular characterization and immunohistochemical localization of palmdelphin, a cytosolic isoform of the paralemmin protein family implicated in membrane dynamics. Eur J Cell Biol 84: 853-66 PubMed GONUTS page
  2. Shiojiri N et al. (1998) Heterogeneous carbamoylphosphate synthetase I expression in testicular transplants of fetal mouse liver. Eur J Cell Biol 75: 389-92 PubMed GONUTS page
  3. Franke H et al. (2005) P2X(7) receptor-mRNA and -protein in the mouse retina; changes during retinal degeneration in BALBCrds mice. Neurochem Int 47: 235-42 PubMed GONUTS page
  4. Iida I et al. (2003) Immunohistochemical localization of hepatocyte growth factor activator (HGFA) in developing mouse liver tissues. Heterogeneous distribution of HGFA protein. J Histochem Cytochem 51: 1139-49 PubMed GONUTS page
  5. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
  6. Chowdhury GM et al. (2007) Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling. J Neurochem 103: 2077-91 PubMed GONUTS page
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