Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Glud1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Glud1 ( synonyms: Gdh-X, Glud )
Protein Name(s) glutamate dehydrogenase 1,
External Links
MGI MGI:95753

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

From MGI

GO:0004352

glutamate dehydrogenase (NAD+) activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P10860

F

From MGI

GO:0004352

glutamate dehydrogenase (NAD+) activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

F

From MGI

GO:0004353

glutamate dehydrogenase (NAD(P)+) activity

MGI:MGI:2157179
PMID:11792727[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004353

glutamate dehydrogenase (NAD(P)+) activity

MGI:MGI:3769241
PMID:16959573[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004353

glutamate dehydrogenase (NAD(P)+) activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

F

From MGI

GO:0005515

protein binding

MGI:MGI:3769241
PMID:16959573[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q8R216

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005525

GTP binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2682130
PMID:14651853[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3769241
PMID:16959573[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P10860

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

C

From MGI

GO:0005743

mitochondrial inner membrane

MGI:MGI:3590069
PMID:12865426[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006520

cellular amino acid metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006095
InterPro:IPR006096
InterPro:IPR006097

P

From MGI

GO:0006537

glutamate biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

P

From MGI

GO:0006538

glutamate catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

P

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006095
InterPro:IPR006096
InterPro:IPR006097

F

From MGI

GO:0019899

enzyme binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P10860

F

From MGI

GO:0032024

positive regulation of insulin secretion

MGI:MGI:3769241
PMID:16959573[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:1922637

P

From MGI

GO:0032024

positive regulation of insulin secretion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

P

From MGI

GO:0043531

ADP binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

F

From MGI

GO:0070403

NAD+ binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

F

From MGI

GO:0070728

leucine binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00367

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Hogenboom S et al. (2002) Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis. J Lipid Res 43: 90-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Haigis MC et al. (2006) SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 126: 941-54 PubMed GONUTS page
  3. Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
  4. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
  5. Da Cruz S et al. (2003) Proteomic analysis of the mouse liver mitochondrial inner membrane. J Biol Chem 278: 41566-71 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox