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MGI:Ghsr
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ghsr | |
| Protein Name(s) | growth hormone secretagogue receptor, | |
| External Links | ||
| MGI | MGI:2441906 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001616 |
growth hormone secretagogue receptor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001616 |
growth hormone secretagogue receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004871 |
signal transducer activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004930 |
G-protein coupled receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:3039217 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1930008 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008154 |
actin polymerization or depolymerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008343 |
adult feeding behavior |
MGI:MGI:3612647 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009725 |
response to hormone stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009755 |
hormone-mediated signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016520 |
growth hormone-releasing hormone receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0017046 |
peptide hormone binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030252 |
growth hormone secretion |
MGI:MGI:3039217 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1930008 |
P |
From MGI |
||
| GO:0032094 |
response to food |
MGI:MGI:3769319 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032100 |
positive regulation of appetite |
MGI:MGI:3612647 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0032691 |
negative regulation of interleukin-1 beta production |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032869 |
cellular response to insulin stimulus |
MGI:MGI:3769319 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042536 |
negative regulation of tumor necrosis factor biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042562 |
hormone binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043005 |
neuron projection |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043134 |
regulation of hindgut contraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043568 |
positive regulation of insulin-like growth factor receptor signaling pathway |
MGI:MGI:3039217 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3040440 |
P |
From MGI |
||
| GO:0045121 |
membrane raft |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045409 |
negative regulation of interleukin-6 biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045923 |
positive regulation of fatty acid metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046676 |
negative regulation of insulin secretion |
MGI:MGI:3709118 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046697 |
decidualization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050728 |
negative regulation of inflammatory response |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051963 |
regulation of synapse assembly |
MGI:MGI:3696310 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3040440 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Sun Y et al. (2004) Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A 101: 4679-84 PubMed GONUTS page
- ↑ 2.0 2.1 Zigman JM et al. (2005) Mice lacking ghrelin receptors resist the development of diet-induced obesity. J Clin Invest 115: 3564-72 PubMed GONUTS page
- ↑ 3.0 3.1 Luque RM & Kineman RD (2006) Impact of obesity on the growth hormone axis: evidence for a direct inhibitory effect of hyperinsulinemia on pituitary function. Endocrinology 147: 2754-63 PubMed GONUTS page
- ↑ Dezaki K et al. (2006) Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance. Diabetes 55: 3486-93 PubMed GONUTS page
- ↑ Abizaid A et al. (2006) Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. J Clin Invest 116: 3229-39 PubMed GONUTS page
