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MGI:Gdf11

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Gdf11 ( synonyms: Bmp11 )
Protein Name(s) growth differentiation factor 11,
External Links
MGI MGI:1338027

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001656

metanephros development

MGI:MGI:2661314
PMID:12729564[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0001657

ureteric bud development

MGI:MGI:2661314
PMID:12729564[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449672

P

From MGI

GO:0005125

cytokine activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0202

F

From MGI

GO:0005515

protein binding

MGI:MGI:3695190
PMID:16845371[2]

IPI: Inferred from Physical Interaction

UniProtKB:P27040

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005615

extracellular space

MGI:MGI:2661314
PMID:12729564[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0008083

growth factor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

From MGI

GO:0008083

growth factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001839
InterPro:IPR001111
InterPro:IPR017948

F

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:3512831
PMID:15548585[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449672

P

From MGI

GO:0009887

organ morphogenesis

MGI:MGI:3512831
PMID:15548585[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449672

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:1339513
PMID:10391213[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449672

P

From MGI

GO:0021512

spinal cord anterior/posterior patterning

MGI:MGI:3701017
PMID:16790475[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449672

P

From MGI

GO:0031016

pancreas development

MGI:MGI:3512831
PMID:15548585[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449672

P

From MGI

GO:0040007

growth

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

From MGI

GO:0045596

negative regulation of cell differentiation

MGI:MGI:3581514
PMID:15976303[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045665

negative regulation of neuron differentiation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:XP_001071574

P

From MGI

GO:0048469

cell maturation

MGI:MGI:3512831
PMID:15548585[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449672

P

From MGI

GO:0048593

camera-type eye morphogenesis

MGI:MGI:3581514
PMID:15976303[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449673

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Esquela AF & Lee SJ (2003) Regulation of metanephric kidney development by growth/differentiation factor 11. Dev Biol 257: 356-70 PubMed GONUTS page
  2. Andersson O et al. (2006) Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis. EMBO Rep 7: 831-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Harmon EB et al. (2004) GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development. Development 131: 6163-74 PubMed GONUTS page
  4. McPherron AC et al. (1999) Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11. Nat Genet 22: 260-4 PubMed GONUTS page
  5. Liu JP (2006) The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord. Development 133: 2865-74 PubMed GONUTS page
  6. 6.0 6.1 Kim J et al. (2005) GDF11 controls the timing of progenitor cell competence in developing retina. Science 308: 1927-30 PubMed GONUTS page
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