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MGI:Gcm2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Gcm2 ( synonyms: Gcm1-rs2 ) | |
| Protein Name(s) | glial cells missing homolog 2 (Drosophila), | |
| External Links | ||
| MGI | MGI:1861438 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:84646 |
ISA: Inferred from Sequence Alignment |
protein_id:AAF52790 |
F |
From MGI |
||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:1860721 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1303190 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3630207 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006874 |
cellular calcium ion homeostasis |
MGI:MGI:1327757 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0006874 |
cellular calcium ion homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:3709788 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1889069 |
P |
From MGI |
||
| GO:0030643 |
cellular phosphate ion homeostasis |
MGI:MGI:1327757 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0030643 |
cellular phosphate ion homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:3709788 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1889069 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:1327757 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0060017 |
parathyroid gland development |
MGI:MGI:1327757 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0060017 |
parathyroid gland development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071310 |
cellular response to organic substance |
MGI:MGI:4460059 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Akiyama Y et al. (1996) The gcm-motif: a novel DNA-binding motif conserved in Drosophila and mammals. Proc Natl Acad Sci U S A 93: 14912-6 PubMed GONUTS page
- ↑ Günther T et al. (2000) Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. Nature 406: 199-203 PubMed GONUTS page
- ↑ Kim J et al. (1998) Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing. Proc Natl Acad Sci U S A 95: 12364-9 PubMed GONUTS page
- ↑ Iwasaki Y et al. (2003) The potential to induce glial differentiation is conserved between Drosophila and mammalian glial cells missing genes. Development 130: 6027-35 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Kanemura Y et al. (1999) Isolation and expression analysis of a novel human homologue of the Drosophila glial cells missing (gcm) gene. FEBS Lett 442: 151-6 PubMed GONUTS page
- ↑ 6.0 6.1 Liu Z et al. (2007) Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. Dev Biol 305: 333-46 PubMed GONUTS page
- ↑ Grigorieva IV et al. (2010) Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2. J Clin Invest 120: 2144-55 PubMed GONUTS page
