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MGI:Gbx2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Gbx2 ( synonyms: Gbx-2, MMoxA, Stra7 )
Protein Name(s) gastrulation brain homeobox 2,
External Links
MGI MGI:95668

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001569

patterning of blood vessels

MGI:MGI:3588904
PMID:15996652[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:99604

P

From MGI

GO:0001569

patterning of blood vessels

MGI:MGI:3588904
PMID:15996652[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0001755

neural crest cell migration

MGI:MGI:3588904
PMID:15996652[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0001755

neural crest cell migration

MGI:MGI:4358009
PMID:19700621[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009057

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005634

nucleus

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

P

From MGI

GO:0007411

axon guidance

MGI:MGI:2179161
PMID:11967891[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0008283

cell proliferation

MGI:MGI:3624192
PMID:16651541[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0021549

cerebellum development

MGI:MGI:3624192
PMID:16651541[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0021555

midbrain-hindbrain boundary morphogenesis

MGI:MGI:3624192
PMID:16651541[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0021568

rhombomere 2 development

MGI:MGI:3624192
PMID:16651541[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0021930

cerebellar granule cell precursor proliferation

MGI:MGI:3624192
PMID:16651541[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0030902

hindbrain development

MGI:MGI:3578572
PMID:15829521[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0030902

hindbrain development

MGI:MGI:3624192
PMID:16651541[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0030917

midbrain-hindbrain boundary development

MGI:MGI:3624192
PMID:16651541[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0035239

tube morphogenesis

MGI:MGI:3588904
PMID:15996652[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0042472

inner ear morphogenesis

MGI:MGI:3578572
PMID:15829521[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0042472

inner ear morphogenesis

MGI:MGI:3588904
PMID:15996652[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

F

From MGI

GO:0048483

autonomic nervous system development

MGI:MGI:3588904
PMID:15996652[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857634

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Byrd NA & Meyers EN (2005) Loss of Gbx2 results in neural crest cell patterning and pharyngeal arch artery defects in the mouse embryo. Dev Biol 284: 233-45 PubMed GONUTS page
  2. Calmont A et al. (2009) Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm. Development 136: 3173-83 PubMed GONUTS page
  3. Hevner RF et al. (2002) Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other. J Comp Neurol 447: 8-17 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Waters ST & Lewandoski M (2006) A threshold requirement for Gbx2 levels in hindbrain development. Development 133: 1991-2000 PubMed GONUTS page
  5. 5.0 5.1 Lin Z et al. (2005) Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling. Development 132: 2309-18 PubMed GONUTS page
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