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MGI:Gbp1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Gbp1 ( synonyms: Gbp-1, Mag-1, Mpa-1, Mpa1 )
Protein Name(s) guanylate binding protein 1,
External Links
MGI MGI:95666

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019002

GMP binding

MGI:MGI:56437
PMID:3927587[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0020005

symbiont-containing vacuole membrane

MGI:MGI:4412460
PMID:18025219[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031410

cytoplasmic vesicle

MGI:MGI:4412460
PMID:18025219[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031410

cytoplasmic vesicle

MGI:MGI:5007562
PMID:21551061[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0035458

cellular response to interferon-beta

MGI:MGI:3836373
PMID:19158679[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042832

defense response to protozoan

MGI:MGI:4412460
PMID:18025219[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050830

defense response to Gram-positive bacterium

MGI:MGI:4412460
PMID:18025219[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050830

defense response to Gram-positive bacterium

MGI:MGI:5007562
PMID:21551061[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0051856

adhesion to symbiont

MGI:MGI:4412460
PMID:18025219[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0071346

cellular response to interferon-gamma

MGI:MGI:4412460
PMID:18025219[2]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Prochazka M et al. (1985) Interferon-induced guanylate-binding proteins: mapping of the murine Gbp-1 locus to chromosome 3. Virology 145: 273-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Degrandi D et al. (2007) Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense. J Immunol 179: 7729-40 PubMed GONUTS page
  3. 3.0 3.1 Kim BH et al. (2011) A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection. Science 332: 717-21 PubMed GONUTS page
  4. Bürckstümmer T et al. (2009) An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 10: 266-72 PubMed GONUTS page
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