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MGI:Gap43

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Gap43 ( synonyms: B-50, Basp2, GAP-43, neuromodulin )
Protein Name(s) growth associated protein 43,
External Links
MGI MGI:95639

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005516

calmodulin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0112

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:3664674
PMID:16892058[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P17677

C

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0007411

axon guidance

MGI:MGI:1353240
PMID:10662636[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2448337

P

From MGI

GO:0010001

glial cell differentiation

MGI:MGI:3531391
PMID:15234344[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2180341

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016198

axon choice point recognition

MGI:MGI:70834
PMID:7859286[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2448337

P

From MGI

GO:0030054

cell junction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030424

axon

MGI:MGI:1344237
PMID:10482234[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030424

axon

MGI:MGI:2183841
PMID:10850491[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030424

axon

MGI:MGI:3042561
PMID:15071120[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031527

filopodium membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P17677

C

From MGI

GO:0040008

regulation of growth

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0341

P

From MGI

GO:0040008

regulation of growth

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001422
InterPro:IPR017454
InterPro:IPR018243

P

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0045165

cell fate commitment

MGI:MGI:3531391
PMID:15234344[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0045202

synapse

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0770

C

From MGI

GO:0051489

regulation of filopodium assembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P17677

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Cappello S et al. (2006) The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nat Neurosci 9: 1099-107 PubMed GONUTS page
  2. Zhang F et al. (2000) GAP-43 mediates retinal axon interaction with lateral diencephalon cells during optic tract formation. Development 127: 969-80 PubMed GONUTS page
  3. 3.0 3.1 Shen Y et al. (2004) Failure to express GAP-43 leads to disruption of a multipotent precursor and inhibits astrocyte differentiation. Mol Cell Neurosci 26: 390-405 PubMed GONUTS page
  4. Strittmatter SM et al. (1995) Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell 80: 445-52 PubMed GONUTS page
  5. Arber S et al. (1999) Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron 23: 659-74 PubMed GONUTS page
  6. Arber S et al. (2000) ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell 101: 485-98 PubMed GONUTS page
  7. Gitler D et al. (2004) Molecular determinants of synapsin targeting to presynaptic terminals. J Neurosci 24: 3711-20 PubMed GONUTS page
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