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MGI:Fxr1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fxr1 ( synonyms: Fxr1h, Fxr1p ) | |
| Protein Name(s) | fragile X mental retardation gene 1, autosomal homolog, | |
| External Links | ||
| MGI | MGI:104860 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002151 |
G-quadruplex RNA binding |
MGI:MGI:3699977 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003723 |
RNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0694 |
F |
From MGI |
||
| GO:0003723 |
RNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR008395 |
F |
From MGI |
||
| GO:0003730 |
mRNA 3'-UTR binding |
MGI:MGI:3573966 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3036554 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3760313 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3573966 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3760313 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005844 |
polysome |
MGI:MGI:3760313 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007517 |
muscle organ development |
MGI:MGI:3046107 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3046846 |
P |
From MGI |
||
| GO:0017148 |
negative regulation of translation |
MGI:MGI:3573966 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0043034 |
costamere |
MGI:MGI:3046107 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
|
NOT |
GO:0002151 |
G-quadruplex RNA binding |
MGI:MGI:3699977 |
IDA: Inferred from Direct Assay |
F |
From MGI |
||
|
NOT |
GO:0002151 |
G-quadruplex RNA binding |
MGI:MGI:3699977 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Bechara E et al. (2007) Fragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structure. Nucleic Acids Res 35: 299-306 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Garnon J et al. (2005) Fragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional level. J Biol Chem 280: 5750-63 PubMed GONUTS page
- ↑ Schenck A et al. (2001) A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P. Proc Natl Acad Sci U S A 98: 8844-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Dubé M et al. (2000) Muscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblast. BMC Genet 1: 4 PubMed GONUTS page
- ↑ 5.0 5.1 Mientjes EJ et al. (2004) Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo. Hum Mol Genet 13: 1291-302 PubMed GONUTS page
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