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MGI:Fto
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fto | |
| Protein Name(s) | fat mass and obesity associated, | |
| External Links | ||
| MGI | MGI:1347093 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001659 |
temperature homeostasis |
MGI:MGI:3840763 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3840763 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4430814 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006307 |
DNA dealkylation involved in DNA repair |
MGI:MGI:3817348 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006307 |
DNA dealkylation involved in DNA repair |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From MGI |
||
| GO:0008198 |
ferrous iron binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0010883 |
regulation of lipid storage |
MGI:MGI:3840763 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0223 |
F |
From MGI |
||
| GO:0035515 |
oxidative RNA demethylase activity |
MGI:MGI:3817348 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0035515 |
oxidative RNA demethylase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035516 |
oxidative DNA demethylase activity |
MGI:MGI:3817348 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0035516 |
oxidative DNA demethylase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035552 |
oxidative single-stranded DNA demethylation |
MGI:MGI:3817348 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035552 |
oxidative single-stranded DNA demethylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035553 |
oxidative single-stranded RNA demethylation |
MGI:MGI:3817348 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035553 |
oxidative single-stranded RNA demethylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0040014 |
regulation of multicellular organism growth |
MGI:MGI:3840763 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042245 |
RNA repair |
MGI:MGI:3817348 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042245 |
RNA repair |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043734 |
DNA-N1-methyladenine dioxygenase activity |
MGI:MGI:4430814 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0043734 |
DNA-N1-methyladenine dioxygenase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0044065 |
regulation of respiratory system process |
MGI:MGI:3840763 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
P |
From MGI |
||
| GO:0060612 |
adipose tissue development |
MGI:MGI:3840763 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070350 |
regulation of white fat cell proliferation |
MGI:MGI:3840763 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070989 |
oxidative demethylation |
MGI:MGI:3817348 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070989 |
oxidative demethylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0080111 |
DNA demethylation |
MGI:MGI:3817348 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0080111 |
DNA demethylation |
MGI:MGI:4430814 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0080111 |
DNA demethylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Fischer J et al. (2009) Inactivation of the Fto gene protects from obesity. Nature 458: 894-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gerken T et al. (2007) The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 318: 1469-72 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Jia G et al. (2008) Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett 582: 3313-9 PubMed GONUTS page
