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MGI:Fst

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Fst
Protein Name(s) follistatin,
External Links
MGI MGI:95586

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19883

P

From MGI

GO:0002244

hemopoietic progenitor cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19883

P

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005634

nucleus

MGI:MGI:4887312
PMID:20032047[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4887312
PMID:20032047[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007276

gamete generation

MGI:MGI:3042808
PMID:15162500[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:98957

P

From MGI

GO:0007389

pattern specification process

MGI:MGI:3513220
PMID:15525533[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857467

P

From MGI

GO:0008585

female gonad development

MGI:MGI:3042808
PMID:15162500[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857467

P

From MGI

GO:0030509

BMP signaling pathway

MGI:MGI:3513220
PMID:15525533[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:88180

P

From MGI

GO:0031069

hair follicle morphogenesis

MGI:MGI:3699694
PMID:12514121[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857467

P

From MGI

GO:0032926

negative regulation of activin receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19883

P

From MGI

GO:0042475

odontogenesis of dentin-containing tooth

MGI:MGI:3050251
PMID:15305290[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857467

P

From MGI

GO:0042475

odontogenesis of dentin-containing tooth

MGI:MGI:3513220
PMID:15525533[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857467

P

From MGI

GO:0043395

heparan sulfate proteoglycan binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P21674

F

From MGI

GO:0043616

keratinocyte proliferation

MGI:MGI:3699694
PMID:12514121[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857467

P

From MGI

GO:0045596

negative regulation of cell differentiation

MGI:MGI:3513220
PMID:15525533[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:88180

P

From MGI

GO:0045596

negative regulation of cell differentiation

MGI:MGI:3513220
PMID:15525533[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857467

P

From MGI

GO:0048185

activin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P19883

F

From MGI

GO:0051798

positive regulation of hair follicle development

MGI:MGI:3699694
PMID:12514121[4]

ISO: Inferred from Sequence Orthology

UniProtKB:P19883

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Kimura F et al. (2010) The follistatin-288 isoform alone is sufficient for survival but not for normal fertility in mice. Endocrinology 151: 1310-9 PubMed GONUTS page
  2. 2.0 2.1 Yao HH et al. (2004) Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn 230: 210-5 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Wang XP et al. (2004) Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell 7: 719-30 PubMed GONUTS page
  4. 4.0 4.1 4.2 Nakamura M et al. (2003) Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin. FASEB J 17: 497-9 PubMed GONUTS page
  5. Wang XP et al. (2004) Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn 231: 98-108 PubMed GONUTS page
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