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MGI:Frzb
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Frzb ( synonyms: fritz, Frp, frzb-1, Sfrp3 ) | |
| Protein Name(s) | frizzled-related protein, | |
| External Links | ||
| MGI | MGI:892032 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001944 |
vasculature development |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:86658 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:707948 |
NAS: Non-traceable Author Statement |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
C |
From MGI |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007420 |
brain development |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
P |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008406 |
gonad development |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
P |
From MGI |
|||
| GO:0010721 |
negative regulation of cell development |
MGI:MGI:4356222 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0879 |
P |
From MGI |
||
| GO:0017147 |
Wnt-protein binding |
MGI:MGI:707948 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030165 |
PDZ domain binding |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
F |
From MGI |
|||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
MGI:MGI:3714704 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98958 |
P |
From MGI |
||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
MGI:MGI:707948 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030308 |
negative regulation of cell growth |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042472 |
inner ear morphogenesis |
MGI:MGI:3823145 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042472 |
inner ear morphogenesis |
MGI:MGI:3823145 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98958 |
P |
From MGI |
||
| GO:0042813 |
Wnt-activated receptor activity |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
F |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045600 |
positive regulation of fat cell differentiation |
MGI:MGI:2385552 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060029 |
convergent extension involved in organogenesis |
MGI:MGI:3714704 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98958 |
P |
From MGI |
||
| GO:0060056 |
mammary gland involution |
MGI:MGI:4459044 |
PANTHER:PTHR11309 |
P |
From MGI |
|||
| GO:0061037 |
negative regulation of cartilage development |
MGI:MGI:3823145 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98958 |
P |
From MGI |
||
| GO:0070367 |
negative regulation of hepatocyte differentiation |
MGI:MGI:4356222 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:4421265 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98956 |
P |
From MGI |
||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090103 |
cochlea morphogenesis |
MGI:MGI:3714704 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98958 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Rattner A et al. (1997) A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci U S A 94: 2859-63 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Mayr T et al. (1997) Fritz: a secreted frizzled-related protein that inhibits Wnt activity. Mech Dev 63: 109-25 PubMed GONUTS page
- ↑ 3.0 3.1 Bi Y et al. (2009) Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem 108: 295-303 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Qian D et al. (2007) Wnt5a functions in planar cell polarity regulation in mice. Dev Biol 306: 121-33 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Liu W et al. (2008) Coordinated molecular control of otic capsule differentiation: functional role of Wnt5a signaling and opposition by sfrp3 activity. Growth Factors 26: 343-54 PubMed GONUTS page
- ↑ Bennett CN et al. (2002) Regulation of Wnt signaling during adipogenesis. J Biol Chem 277: 30998-1004 PubMed GONUTS page
- ↑ Alfieri CM et al. (2010) Wnt signaling in heart valve development and osteogenic gene induction. Dev Biol 338: 127-35 PubMed GONUTS page
