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MGI:Fmr1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fmr1 ( synonyms: Fmr-1, FMRP ) | |
| Protein Name(s) | fragile X mental retardation syndrome 1 homolog, | |
| External Links | ||
| MGI | MGI:95564 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003723 |
RNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_434691 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3036554 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4418608 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2657099 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005845 |
mRNA cap binding complex |
MGI:MGI:4418608 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0007417 |
central nervous system development |
MGI:MGI:2657099 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2451086 |
P |
From MGI |
||
| GO:0019717 |
synaptosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_434691 |
C |
From MGI |
||
| GO:0030425 |
dendrite |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_434691 |
C |
From MGI |
||
| GO:0043197 |
dendritic spine |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_434691 |
C |
From MGI |
||
| GO:0043198 |
dendritic shaft |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_434691 |
C |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_434691 |
C |
From MGI |
||
| GO:0045947 |
negative regulation of translational initiation |
MGI:MGI:4418608 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051028 |
mRNA transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0509 |
P |
From MGI |
||
|
colocalizes_with |
GO:0005844 |
polysome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_434691 |
C |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Schenck A et al. (2001) A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P. Proc Natl Acad Sci U S A 98: 8844-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Napoli I et al. (2008) The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP. Cell 134: 1042-54 PubMed GONUTS page
- ↑ 3.0 3.1 Willemsen R et al. (2003) The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome. Hum Mol Genet 12: 949-59 PubMed GONUTS page
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