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MGI:Fgfrl1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fgfrl1 ( synonyms: FGFR5, FGFR5beta, FGFR5gamma, fibroblast growth factor receptor 5 ) | |
| Protein Name(s) | fibroblast growth factor receptor-like 1, | |
| External Links | ||
| MGI | MGI:2150920 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001501 |
skeletal system development |
MGI:MGI:3848851 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3849002 |
P |
From MGI |
||
| GO:0001571 |
non-tyrosine kinase fibroblast growth factor receptor activity |
MGI:MGI:2148330 |
ISA: Inferred from Sequence Alignment |
EMBL:M28998 |
F |
From MGI |
||
| GO:0003179 |
heart valve morphogenesis |
MGI:MGI:3848851 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3849002 |
P |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005007 |
fibroblast growth factor-activated receptor activity |
MGI:MGI:2673744 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005007 |
fibroblast growth factor-activated receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:2673744 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005887 |
integral to plasma membrane |
MGI:MGI:2148330 |
ISA: Inferred from Sequence Alignment |
EMBL:M28998 |
C |
From MGI |
||
| GO:0007166 |
cell surface receptor signaling pathway |
MGI:MGI:2148330 |
ISA: Inferred from Sequence Alignment |
EMBL:M28998 |
P |
From MGI |
||
| GO:0008201 |
heparin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:2673744 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008543 |
fibroblast growth factor receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0017134 |
fibroblast growth factor binding |
MGI:MGI:2148330 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0017134 |
fibroblast growth factor binding |
MGI:MGI:2673744 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0040037 |
negative regulation of fibroblast growth factor receptor signaling pathway |
MGI:MGI:2148330 |
IC: Inferred by Curator |
GO:0001571 GO:0017134 |
P |
From MGI |
||
| GO:0060412 |
ventricular septum morphogenesis |
MGI:MGI:3848851 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3849002 |
P |
From MGI |
||
| GO:0060539 |
diaphragm development |
MGI:MGI:3771403 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3771861 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Catela C et al. (2009) Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null mice. Dis Model Mech 2: 283-94 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Sleeman M et al. (2001) Identification of a new fibroblast growth factor receptor, FGFR5. Gene 271: 171-82 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Trueb B et al. (2003) Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues. J Biol Chem 278: 33857-65 PubMed GONUTS page
- ↑ Baertschi S et al. (2007) Mice with a targeted disruption of the Fgfrl1 gene die at birth due to alterations in the diaphragm. FEBS J 274: 6241-53 PubMed GONUTS page
