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MGI:Fgf23
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Fgf23 | |
| Protein Name(s) | fibroblast growth factor 23, | |
| External Links | ||
| MGI | MGI:1891427 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005104 |
fibroblast growth factor receptor binding |
MGI:MGI:3640642 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005105 |
type 1 fibroblast growth factor receptor binding |
MGI:MGI:3696596 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3696596 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0008083 |
growth factor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0339 |
F |
From MGI |
||
| GO:0008083 |
growth factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0008543 |
fibroblast growth factor receptor signaling pathway |
MGI:MGI:3640642 |
IPI: Inferred from Physical Interaction |
P |
From MGI |
|||
| GO:0010966 |
regulation of phosphate transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010980 |
positive regulation of vitamin D 24-hydroxylase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030500 |
regulation of bone mineralization |
MGI:MGI:3510566 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3512143 |
P |
From MGI |
||
| GO:0030502 |
negative regulation of bone mineralization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030643 |
cellular phosphate ion homeostasis |
MGI:MGI:3510566 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3512143 |
P |
From MGI |
||
| GO:0042369 |
vitamin D catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0044421 |
extracellular region part |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_570110 |
C |
From MGI |
||
| GO:0045668 |
negative regulation of osteoblast differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:3696596 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046888 |
negative regulation of hormone secretion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_570110 |
P |
From MGI |
||
| GO:0055062 |
phosphate ion homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
MGI:MGI:3696596 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090080 |
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway |
MGI:MGI:3640642 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1101771 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Kurosu H et al. (2006) Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 281: 6120-3 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Urakawa I et al. (2006) Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 444: 770-4 PubMed GONUTS page
- ↑ 3.0 3.1 Sitara D et al. (2004) Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice. Matrix Biol 23: 421-32 PubMed GONUTS page
